Hevert-Arzneimittel Agarose,Blocking,Epiquik ILC3, eine zentrale angeborene Immunkomponente

ILC3, eine zentrale angeborene Immunkomponente

Mai 1, 2021Mai 1, 2021 MarcusMarcus 0 Comments 10:26 am
hvr-ev

ILC3, eine zentrale angeborene Immunkomponente der Darm-Gehirn-Achse bei Multipler Sklerose 

Intestine immune cells have been more and more appreciated as vital gamers within the central nervous system (CNS) autoimmunity in animal fashions of a number of sclerosis (MS). Among the many intestine immune cells, innate lymphoid cell kind 3 (ILC3) is of particular curiosity in MS analysis, as they symbolize the innate cell counterpart of the foremost pathogenic cell inhabitants in MS, i.e. T helper (Th)17 cells.

Importantly, these cells have been proven to stimulate regulatory T cells (Treg) and to counteract pathogenic Th17 cells in animal fashions of autoimmune illnesses. In addition to, they’re additionally well-known for his or her means to stabilize the intestinal barrier and to form the immune response to the intestine microbiota. Thus, correct upkeep of the intestinal barrier and the institution of the regulatory milieu within the intestine carried out by ILC3 could forestall activation of CNS antigen-specific Th17 cells by the molecular mimicry. Latest findings on the function of ILC3 within the gut-CNS axis and their relevance for MS pathogenesis will probably be mentioned on this paper. Prospects of ILC3 useful modulation for the advantage of MS sufferers will probably be addressed, as effectively.

hvr-ev

hvr-ev

AIRE Antibody
ABF5471 100 ug
EUR 525.6

AIRE Antibody
ABF0334 100 ug
EUR 525.6

AIRE Antibody
ABD6603 100 ug
EUR 525.6

AIRE Antibody
8C10123 50ug
EUR 368
Description: AIRE Antibody

AIRE antibody
70R-33714 100 ug
EUR 294
Description: Rabbit polyclonal AIRE antibody

AIRE antibody
70R-34455 100 ug
EUR 294
Description: Rabbit polyclonal AIRE antibody

AIRE antibody
70R-51449 100 ul
EUR 242
Description: Purified Polyclonal AIRE antibody

AIRE Antibody
33590 100ul
EUR 319

AIRE Antibody
33590-100ul 100ul
EUR 302.4

AIRE Antibody
33590-50ul 50ul
EUR 224.4

AIRE Antibody
ABD3026 100 ug
EUR 525.6

AIRE Antibody
32424 100ul
EUR 439

AIRE Antibody
32424-100ul 100ul
EUR 302.4

AIRE Antibody
CSB-PA274868- each
EUR 402
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

AIRE Antibody
CSB-PA274868-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

AIRE Antibody
1-CSB-PA000839
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  • 50ug
  • 100ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IF, ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/10000

AIRE Antibody
1-CSB-PA001502HA01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

AIRE Antibody
CSB-PA001502KA01HU- each
EUR 402
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

AIRE Antibody
CSB-PA001502KA01HU-100ul 100ul
EUR 466.8
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

AIRE Antibody
1-CSB-PA009261
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  • 50ug
  • 100ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

AIRE Antibody
DF6603 200ul
EUR 420

AIRE Antibody
DF6603-100ul 100ul
EUR 168
Description: WB,IHC,IF/ICC,ELISA(peptide)

AIRE Antibody
DF6603-200ul 200ul
EUR 210
Description: WB,IHC,IF/ICC,ELISA(peptide)

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AF0334 200ul
EUR 420

AIRE Antibody
AF0334-100ul 100ul
EUR 168
Description: WB,IF/ICC,ELISA(peptide)

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AF0334-200ul 200ul
EUR 210
Description: WB,IF/ICC,ELISA(peptide)

AIRE Antibody
E033590 100μg/100μl
EUR 255
Description: Available in various conjugation types.

AIRE Antibody
AF6841 100ul
EUR 420

AIRE Antibody
AF6841-100ul 100ul
EUR 168
Description: ELISA(peptide)

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AF6841-200ul 200ul
EUR 210
Description: ELISA(peptide)

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DF3026 200ul
EUR 420

AIRE Antibody
DF3026-100ul 100ul
EUR 168
Description: WB,IF/ICC,ELISA(peptide)

AIRE Antibody
DF3026-200ul 200ul
EUR 210
Description: WB,IF/ICC,ELISA(peptide)

AIRE Antibody
E11-10123C 100μg
EUR 225
Description: Available in various conjugation types.

AIRE Antibody
E91767 100ul
EUR 255
Description: Available in various conjugation types.

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E300422 100ug/200ul
EUR 275
Description: Available in various conjugation types.

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GWB-9ECF95 0.05 mg Ask for price

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E38PA3130 100ul
EUR 225
Description: Available in various conjugation types.

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E19-3026 100μg/100μl
EUR 225
Description: Available in various conjugation types.

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E18-0334-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

AIRE Antibody
E18-0334-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

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E18-5471-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

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E18-5471-2 100μg/100μl
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Description: Available in various conjugation types.

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MBS5316066-5x01mL 5x0.1mL
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EUR 2015

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MBS2530179-006mL 0.06mL
EUR 190

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MBS2530179-5x02mL 5x0.2mL
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MBS7043864-005mg 0.05mg
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MBS7043864-5x01mg 5x0.1mg
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MBS7132185-01mL 0.1mL
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MBS7132185-5x01mL 5x0.1mL
EUR 1200

AIRE Antibody
MBS7115912-005mg 0.05mg
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AIRE Antibody
MBS7115912-01mg 0.1mg
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MBS7115912-5x01mg 5x0.1mg
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MBS7119602-005mg 0.05mg
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MBS7119602-01mg 0.1mg
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MBS7119602-5x01mg 5x0.1mg
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MBS8510825-005mg 0.05mg
EUR 235

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MBS8510825-01mg 0.1mg
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MBS8510825-01mLAF405M 0.1mL(AF405M)
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MBS8510825-01mLAF750 0.1mL(AF750)
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MBS8513764-01mLAF405L 0.1mL(AF405L)
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MBS8513764-01mLAF405S 0.1mL(AF405S)
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MBS8513764-01mLAF610 0.1mL(AF610)
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MBS8513764-01mLAF635 0.1mL(AF635)
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AIRE Antibody
MBS8512097-005mg 0.05mg
EUR 235

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MBS8512097-01mg 0.1mg
EUR 305

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MBS8512097-01mLAF405M 0.1mL(AF405M)
EUR 465

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MBS8512097-01mLAF546 0.1mL(AF546)
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AIRE Antibody
MBS8512097-01mLAF750 0.1mL(AF750)
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AIRE Antibody
MBS8502406-01mL 0.1mL
EUR 325

AIRE Antibody
MBS8502406-01mLAF405L 0.1mL(AF405L)
EUR 565

AIRE Antibody
MBS8502406-01mLAF405S 0.1mL(AF405S)
EUR 565

AIRE Antibody
MBS8502406-01mLAF610 0.1mL(AF610)
EUR 565

AIRE Antibody
MBS8502406-01mLAF635 0.1mL(AF635)
EUR 565

AIRE Antibody
MBS9405385-005mL 0.05mL
EUR 300

AIRE Antibody
MBS9405385-01mL 0.1mL
EUR 390

AIRE Antibody
MBS9405385-5x01mL 5x0.1mL
EUR 1610

AIRE Antibody
MBS8581750-01mL 0.1mL
EUR 305

AIRE Antibody
MBS8581750-01mLAF405L 0.1mL(AF405L)
EUR 465

AIRE Antibody
MBS8581750-01mLAF405S 0.1mL(AF405S)
EUR 465

AIRE Antibody
MBS8581750-01mLAF610 0.1mL(AF610)
EUR 465

AIRE Antibody
MBS8581750-01mLAF635 0.1mL(AF635)
EUR 465

AIRE Antibody
MBS9607259-01mL 0.1mL
EUR 260

AIRE Antibody
MBS9607259-02mL 0.2mL
EUR 305

AIRE Antibody
MBS9607259-5x02mL 5x0.2mL
EUR 1220

AIRE Antibody
MBS9504440-005mL 0.05mL
EUR 285

AIRE Antibody
MBS9504440-01mL 0.1mL
EUR 385

AIRE Antibody
MBS9504440-5x01mL 5x0.1mL
EUR 1590

AIRE Antibody
MBS9504837-005mL 0.05mL
EUR 285

AIRE Antibody
MBS9504837-01mL 0.1mL
EUR 385

AIRE Antibody
MBS9504837-5x01mL 5x0.1mL
EUR 1590

AIRE Antibody
MBS9613862-01mL 0.1mL
EUR 260

AIRE Antibody
MBS9613862-02mL 0.2mL
EUR 305

AIRE Antibody
MBS9613862-5x02mL 5x0.2mL
EUR 1220

AIRE Antibody
MBS9604490-01mL 0.1mL
EUR 260

AIRE Antibody
MBS9604490-02mL 0.2mL
EUR 305

AIRE Antibody
MBS9604490-5x02mL 5x0.2mL
EUR 1220

AIRE Antibody
MBS9600268-01mL 0.1mL
EUR 260

AIRE Antibody
MBS9600268-02mL 0.2mL
EUR 305

AIRE Antibody
MBS9600268-5x02mL 5x0.2mL
EUR 1220

AIRE Antibody
MBS9414839-005mL 0.05mL
EUR 245

AIRE Antibody
MBS9414839-01mL 0.1mL
EUR 305

AIRE Antibody
MBS9414839-5x01mL 5x0.1mL
EUR 1230

AIRE Antibody
MBS855452-01mg 0.1mg
EUR 305

AIRE Antibody
MBS855452-01mLAF405L 0.1mL(AF405L)
EUR 465

AIRE Antibody
MBS855452-01mLAF405S 0.1mL(AF405S)
EUR 465

AIRE Antibody
MBS855452-01mLAF610 0.1mL(AF610)
EUR 465

AIRE Antibody
MBS855452-01mLAF635 0.1mL(AF635)
EUR 465

AIRE Antibody
MBS856060-01mg 0.1mg
EUR 345

AIRE Antibody
MBS856060-01mLAF405L 0.1mL(AF405L)
EUR 565

AIRE Antibody
MBS856060-01mLAF405S 0.1mL(AF405S)
EUR 565

AIRE Antibody
MBS856060-01mLAF610 0.1mL(AF610)
EUR 565

AIRE Antibody
MBS856060-01mLAF635 0.1mL(AF635)
EUR 565

Anti-Autoimmune regulator (AIRE) Antibody
R1107-1 100ul
EUR 189
Description: The Autoimmune Regulator (AIRE) is a human transcription factor expressed at higher level in thymus, pancreas, adrenal cortex, and testis. It is expressed at lower level in the spleen, fetal liver and lymph nodes. It contains zinc finger motifs and isoform 1 is localized to both the nucleus and cytoplasm. Three splice variant mRNAs products have been described. In the thymus it causes transcription of a wide selection of organ-specific genes which create proteins that are usually only expressed in peripheral tissues, creating an "immunological self-shadow" in the thymus. Defects in AIRE are a cause of autoimmune poly-endocrinopathy candidiasis ectodermal dystrophy (APECED), also known as autoimmune polyglandular syndrome type I (APS-1).

Anti-Autoimmune regulator (AIRE) Antibody
R1305-5 100ul
EUR 189
Description: The Autoimmune Regulator (AIRE) is a human transcription factor expressed at higher level in thymus, pancreas, adrenal cortex, and testis. It is expressed at lower level in the spleen, fetal liver and lymph nodes. It contains zinc finger motifs and isoform 1 is localized to both the nucleus and cytoplasm. Three splice variant mRNAs products have been described. In the thymus it causes transcription of a wide selection of organ-specific genes which create proteins that are usually only expressed in peripheral tissues, creating an "immunological self-shadow" in the thymus. Defects in AIRE are a cause of autoimmune poly-endocrinopathy candidiasis ectodermal dystrophy (APECED), also known as autoimmune polyglandular syndrome type I (APS-1).

AIRE antibody (pAb)
MBS388778-001mL 0.01mL
EUR 205

AIRE antibody (pAb)
MBS388778-01mL 0.1mL
EUR 595

AIRE antibody (pAb)
MBS388778-5x01mL 5x0.1mL
EUR 2600

AIRE-1 Antibody
B8286-100ul 100μl
EUR 217
Description: AIRE-1 Rabbit Polyclonal Antibody

AIRE-1 Antibody
B8286-50ul 50μl
EUR 143.5
Description: AIRE-1 Rabbit Polyclonal Antibody

AIRE-1 Antibody
C10123-100ul 100μl
EUR 217
Description: AIRE-1 Rabbit Polyclonal Antibody

AIRE-1 Antibody
C10123-50ul 50μl
EUR 143.5
Description: AIRE-1 Rabbit Polyclonal Antibody

AIRE antibody (Ser156)
70R-34454 100 ug
EUR 294
Description: Rabbit polyclonal AIRE antibody (Ser156)

AIRE Antibody (Center)
E45R30724G-1 100 ul
EUR 395

AIRE Antibody (Center)
E45R30724G-4 50 ul
EUR 295

AIRE Antibody (Center)
MBS9209601-008mL 0.08mL
EUR 210

AIRE Antibody (Center)
MBS9209601-04mL 0.4mL
EUR 430

AIRE Antibody (Center)
MBS9209601-5x04mL 5x0.4mL
EUR 1910

Polyclonal AIRE Antibody
APR03336G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AIRE . This antibody is tested and proven to work in the following applications:

AIRE antibody - middle region
MBS3200674-01mL 0.1mL
EUR 455

AIRE antibody - middle region
MBS3200674-5x01mL 5x0.1mL
EUR 1995

AIRE antibody - middle region
MBS3203843-01mL 0.1mL
EUR 455

AIRE antibody - middle region
MBS3203843-5x01mL 5x0.1mL
EUR 1995

AIRE Antibody, HRP conjugated
1-CSB-PA001502HB01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

AIRE Antibody, HRP conjugated
MBS7046218-005mg 0.05mg
EUR 190

AIRE Antibody, HRP conjugated
MBS7046218-01mg 0.1mg
EUR 270

AIRE Antibody, HRP conjugated
MBS7046218-5x01mg 5x0.1mg
EUR 1205

AIRE Antibody, FITC conjugated
1-CSB-PA001502HC01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

AIRE Antibody, FITC conjugated
MBS7045530-005mg 0.05mg
EUR 190

AIRE Antibody, FITC conjugated
MBS7045530-01mg 0.1mg
EUR 270

AIRE Antibody, FITC conjugated
MBS7045530-5x01mg 5x0.1mg
EUR 1205

OACA09334-50UG - AIRE Antibody
OACA09334-50UG 50ug
EUR 179

AIRE (pS156) Antibody
abx332932-100g 100 µg Ask for price

AIRE (pS156) Antibody
abx332932-100ul 100 ul
EUR 560.4

AIRE (pS156) Antibody
abx332932-20g 20 µg
EUR 412.5

AIRE (pS156) Antibody
abx332932-50g 50 µg Ask for price

AIRE Antibody, Biotin conjugated
1-CSB-PA001502HD01HU
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  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

AIRE Antibody, Biotin conjugated
MBS7044224-005mg 0.05mg
EUR 190

AIRE Antibody, Biotin conjugated
MBS7044224-01mg 0.1mg
EUR 270

AIRE Antibody, Biotin conjugated
MBS7044224-5x01mg 5x0.1mg
EUR 1205

OAAJ03874-100UL - AIRE Antibody
OAAJ03874-100UL 100uL
EUR 319

OAAJ07077-100UL - AIRE Antibody
OAAJ07077-100UL 100uL
EUR 319

OAEB02079-100UG - AIRE Antibody
OAEB02079-100UG 100ug
EUR 349

Vibrio cholerae Sialidase-spezifische Immunantworten sind mit dem Schutz gegen Cholera verbunden 

Cholera stays a significant public well being drawback in resource-limited nations. Vaccination is a vital technique to stop cholera, however presently obtainable vaccines present solely Three to five years of safety. Understanding immune responses to cholera antigens in naturally contaminated people could elucidate which of those are key to longer-term safety seen following an infection. We not too long ago recognized Vibrio cholerae O1 sialidase, a neuraminidase that facilitates binding of cholera toxin to intestinal epithelial cells, as immunogenic following an infection in two current high-throughput screens.

Right here, we current systemic, mucosal, and reminiscence immune responses to sialidase in cholera index circumstances and evaluated whether or not systemic responses to sialidase correlated with safety utilizing a cohort of family contacts. Total, we discovered age-related variations in antisialidase immune response following cholera. Adults developed important plasma anti-sialidase IgA, IgG, and IgM responses following an infection, whereas older youngsters (≥5 years) developed each IgG and IgM responses, and youthful youngsters solely developed IgM responses.

Neither older youngsters nor youthful youngsters had an increase in IgA responses over the convalescent section of an infection (day 7/day 30). On analysis of mucosal responses and reminiscence B-cell responses to sialidase, we discovered adults developed IgA antibody-secreting cell (ASC) and reminiscence B-cell responses. Lastly, in family contacts, the presence of serum anti-sialidase IgA, IgG, and IgM antibodies at enrollment was related to a lower within the danger of subsequent an infection. These knowledge present cholera sufferers develop age-related immune responses in opposition to sialidase and recommend that immune responses that concentrate on sialidase could contribute to protecting immunity in opposition to cholera.IMPORTANCE Cholera an infection can lead to extreme dehydration which will result in demise inside a brief time frame if not handled instantly. Vaccination is a vital technique to stop the illness. Oral cholera vaccines present Three to five years of safety, with 60% protecting efficacy, whereas pure an infection supplies longer-term safety than vaccination.

Understanding the immune responses after pure an infection is vital to raised perceive immune responses to antigens that mediate longer-term safety. Sialidase is a neuraminidase that facilitates binding of cholera toxin to intestinal epithelial cells. We present right here that sufferers with cholera develop systemic, mucosal, and reminiscence B-cell immune responses to the sialidase antigen of Vibrio cholerae O1 and that plasma responses concentrating on this antigen correlate with safety.

Genexpressions- und DNA-Methylierungsanalysen legen nahe, dass zwei immunverwandte Gene prognostische Faktoren für Darmkrebs sind 

Background: Colorectal most cancers (CRC) is the second most prevalent most cancers, because it accounts for roughly 10% of all yearly recognized cancers. Research have indicated that DNA methylation is concerned in most cancers genesis. The aim of this examine was to analyze the relationships amongst DNA methylation, gene expression and the tumor-immune microenvironment of CRC, and eventually, to determine potential key genes associated to immune cell infiltration in CRC.

Strategies: Within the current examine, we used the ChAMP and DESeq2 packages, correlation analyses, and Cox regression analyses to determine immune-related differentially expressed genes (IR-DEGs) that had been correlated with aberrant methylation and to assemble a danger evaluation mannequin.

Outcomes: Lastly, we discovered that HSPA1A expression and CCRL2 expression had been positively and negatively related to the danger rating of CRC, respectively. Sufferers within the high-risk group had been extra positively correlated with some varieties of tumor-infiltrating immune cells, whereas they had been negatively correlated with different tumor-infiltrating immune cells. After the sufferers had been regrouped in accordance with the median danger rating, we might extra successfully distinguish them based mostly on survival final result, clinicopathological traits, particular tumor-immune infiltration standing and extremely expressed immune-related biomarkers.

Conclusion: This examine advised that the danger evaluation mannequin constructed by pairing immune-related differentially expressed genes correlated with aberrant DNA methylation might predict the result of CRC sufferers and would possibly assist to determine these sufferers who may benefit from antitumor immunotherapy.

Assoziation von Polymorphismen in Genen, die an der Schmelzbildung, der Geschmackspräferenz und der Immunantwort beteiligt sind, mit Karies im frühen Kindesalter bei saudischen Vorschulkindern 

Dental caries is primarily elicited by modifiable components reminiscent of insufficient oral hygiene, poor dietary practices and poor fluoride publicity. Nonetheless, there’s a rising physique of proof suggesting the profound affect of genetic components in dental caries susceptibility. The current examine aimed to guage the affiliation between single nucleotide polymorphisms (SNPs) in ENAM (rs12640848), MMP20 (rs1784418), TAS2R38 (rs713598), and LTF (rs4547741) genes and early childhood caries (ECC) in Saudi preschool youngsters.

This case-control examine enrolled 360 Saudi preschool youngsters (262 with ECC and 98 caries-free). Information on environmental components had been collected by a questionnaire. Nonetheless, caries expertise and oral hygiene knowledge had been obtained throughout scientific examination. Buccal swab samples had been collected for DNA extraction and SNPs had been genotyped utilizing PCR and DNA sequencing. Youngsters with ECC had been in comparison with caries free youngsters (management), then they had been categorized into two classes based mostly on ECC severity as follows; non-severe ECC (NS-ECC), and severe-ECC (S-ECC). Affiliation between the SNPs, ECC, NS-ECC, and S-ECC was reported as an odds ratio (OR) with a 95% confidence interval (CI). The vast majority of the youngsters (72.8%) exhibited ECC (31.7% NS-ECC and 41.1% S-ECC) with imply dmft of 4.20 ± 4.05. Multivariate analyses of environmental components confirmed that nocturnal feeding was a danger issue for ECC (P = 0.008). Poor oral hygiene was additionally a danger issue for each NS-ECC and S-ECC (ECC: P < 0.0001, NS-ECC: P = 0.032 and S-ECC: P < 0.0001).

Univariate evaluation confirmed that the AG genotype of rs1784418 of MMP20 gene was protecting in opposition to ECC (OR = 0.532; 95% CI = 0.316-0.897, P = 0.018) and in opposition to NS-ECC (OR = 0.436; 95% CI = 0.238-0.798, P = 0.007). When environmental danger components for ECC had been included as covariates throughout multivariate evaluation, AG variant in rs1784418 of MMP20 gene remained much less frequent in NS-ECC circumstances in comparison with controls with borderline significance (OR = 0.542; 95% CI = 0.285-1.033, P = 0.063). Our findings concluded that MMP20 rs1784418 SNP could be related to safety in opposition to ECC in Saudi preschool youngsters.

TCIRG1 (NM_006053) Human Over-expression Lysate
E45H07999-2 each
EUR 395

TCIRG1 (NM_006019) Human Over-expression Lysate
E45H08014-2 each
EUR 395

TCIRG1 (NM_006019) Human Over-expression Lysate
LS010312 100ug
EUR 628
Description: Transient overexpression lysate of T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 (TCIRG1), transcript variant 1

Myelin expression factor 2 (MYEF2) (NM_016132) Human Over-expression Lysate
E45H09950-2 each
EUR 395

Myelin expression factor 2 (MYEF2) (NM_016132) Human Over-expression Lysate
LS050804 100ug
EUR 960
Description: Transient overexpression lysate of myelin expression factor 2 (MYEF2)

baculoCOMPLETE protein expression kit
400100 5 reactions
EUR 621.81

baculoCOMPLETE protein expression kit + baculoQUANT all-in-one
400101 5 + 100 reactions
EUR 1009.89

Human TCIRG1 Protein Lysate
MBS8428363-INQUIRE INQUIRE Ask for price

Human TCIRG1 Protein Lysate 20ug
IHUTCIRG1PLLY20UG each
EUR 211
Description: Human TCIRG1 Protein Lysate 20ug

OCOA12297-20UG - TCIRG1 Protein Lysate
OCOA12297-20UG 20ug
EUR 169

OCOA12312-20UG - TCIRG1 Protein Lysate
OCOA12312-20UG 20ug
EUR 169

TCIRG1
CSB-CL615690HU 10 μg plasmid + 200μl Glycerol Ask for price

TCIRG1
MBS8564501-01mLAF405L 0.1mL(AF405L)
EUR 565

TCIRG1
MBS8564501-01mLAF405S 0.1mL(AF405S)
EUR 565

TCIRG1
MBS8564501-01mLAF610 0.1mL(AF610)
EUR 565

TCIRG1
MBS8564501-01mLAF635 0.1mL(AF635)
EUR 565

TCIRG1
MBS8564501-02mL 0.2mL
EUR 345

TCIRG1 Peptide
6973P 0.05 mg
EUR 197.7
Description: (NT) TCIRG1 peptide

TCIRG1 Peptide
MBS152543-005mg 0.05mg
EUR 175

TCIRG1 Peptide
MBS152543-5x005mg 5x0.05mg
EUR 770

TCIRG1 Antibody
6973-002mg 0.02 mg
EUR 206.18
Description: TCIRG1 Antibody: The T-cell immune regulator 1 (TCIRG1) is the a3 subunit of the vacuolar-type proton transporting ATPase (V-ATPase), a proton pump in late endosomes and lysosomes that functions in the luminal acidification of these organelles. Genetic defects in the gene encoding this protein a responsible for a severe form of autosomal recessive osteopetrosis, a condition that leads to increased bone density, decreased bone strength, and inflammation in bone tissues. TCIRG1 is also required for the normal secretion of insulin and the bacteria-killing function of macrophages.

TCIRG1 Antibody
6973-01mg 0.1 mg
EUR 523.7
Description: TCIRG1 Antibody: The T-cell immune regulator 1 (TCIRG1) is the a3 subunit of the vacuolar-type proton transporting ATPase (V-ATPase), a proton pump in late endosomes and lysosomes that functions in the luminal acidification of these organelles. Genetic defects in the gene encoding this protein a responsible for a severe form of autosomal recessive osteopetrosis, a condition that leads to increased bone density, decreased bone strength, and inflammation in bone tissues. TCIRG1 is also required for the normal secretion of insulin and the bacteria-killing function of macrophages.

TCIRG1 antibody
70R-20741 50 ul
EUR 289
Description: Rabbit polyclonal TCIRG1 antibody

TCIRG1 Antibody
25518 100ul
EUR 479

TCIRG1 Antibody
25518-100ul 100ul
EUR 468

TCIRG1 Antibody
1-CSB-PA615690LA01HU
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against TCIRG1. Recognizes TCIRG1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200

TCIRG1 Antibody
DF13909 100ul
EUR 420

TCIRG1 Antibody
DF13909-100ul 100ul
EUR 168
Description: ELISA(peptide)

TCIRG1 Antibody
DF13909-200ul 200ul
EUR 210
Description: ELISA(peptide)

TCIRG1 Antibody
CAC11499-100ug 100ug
EUR 314

TCIRG1 Antibody
CAC11499-50ug 50ug
EUR 199.2

TCIRG1 Antibody
1-CSB-PA023312GA01HU
  • Ask for price
  • Ask for price
  • 50ul
  • 150ul
Description: A polyclonal antibody against TCIRG1. Recognizes TCIRG1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

TCIRG1 Antibody
E312960 200ul
EUR 275
Description: Available in various conjugation types.

TCIRG1 Antibody
MBS150138-01mg 0.1mg
EUR 445

TCIRG1 Antibody
MBS150138-5x01mg 5x0.1mg
EUR 1965

TCIRG1 Antibody
MBS7110103-005mg 0.05mg
EUR 190

TCIRG1 Antibody
MBS7110103-01mg 0.1mg
EUR 270

TCIRG1 Antibody
MBS7110103-5x01mg 5x0.1mg
EUR 1205

TCIRG1 Antibody
MBS9631581-1mg 1mg
EUR 375

TCIRG1 Antibody
MBS9631581-5x1mg 5x1mg
EUR 1545

TCIRG1 Antibody
MBS9629198-01mL 0.1mL
EUR 260

TCIRG1 Antibody
MBS9629198-02mL 0.2mL
EUR 305

TCIRG1 Antibody
MBS9629198-5x02mL 5x0.2mL
EUR 1220

TCIRG1 Antibody
MBS9400716-01mL 0.1mL
EUR 495

TCIRG1 Antibody
MBS9400716-5x01mL 5x0.1mL
EUR 2075

EP Reagent Biuret Reagent - 100ML
1011601 1L
EUR 59.4

PEROXIDE BLOCKING REAGENT Reagent
GWB-Q00308 50 ml Ask for price

TCIRG1 Rabbit mAb
A24945 50μL
EUR 226.72

TCIRG1 Rabbit pAb
A15382 50μL
EUR 173.58

TCIRG1 Rabbit pAb
A15382-100ul 100 ul
EUR 369.6

TCIRG1 Rabbit pAb
A15382-200ul 200 ul
EUR 550.8

TCIRG1 Rabbit pAb
A15382-20ul 20 ul
EUR 219.6

TCIRG1 Rabbit pAb
A15382-50ul 50 ul
EUR 267.6

TCIRG1 cDNA Clone
MBS1270970-001mgPlasmid02mLGlycerolStock 0.01mgPlasmid+0.2mLGlycerol-Stock
EUR 780

TCIRG1 cDNA Clone
MBS1270970-5x001mgPlasmid5x02mLGlycerolStock 5x0.01mgPlasmid+5x0.2mLGlycerol-Stock
EUR 3455

TCIRG1 Rabbit pAb
E2515382 100ul
EUR 225
Description: Available in various conjugation types.

TCIRG1 Rabbit pAb
E45R21941N 50 ul
EUR 297.75

TCIRG1 Rabbit pAb
MBS8549885-01mL 0.1mL
EUR 305

TCIRG1 Rabbit pAb
MBS8549885-01mLAF405L 0.1mL(AF405L)
EUR 565

TCIRG1 Rabbit pAb
MBS8549885-01mLAF405S 0.1mL(AF405S)
EUR 565

TCIRG1 Rabbit pAb
MBS8549885-01mLAF610 0.1mL(AF610)
EUR 565

TCIRG1 Rabbit pAb
MBS8549885-01mLAF635 0.1mL(AF635)
EUR 565

EP Reagent Iodoplatinate Reagent - 200ML
1046300 200ML
EUR 502.2

EP Reagent Molybdovanadic Reagent - 100ML
1056700 100ML
EUR 59.4

Human TCIRG1 siRNA
20-abx936356
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

TCIRG1 siRNA (Human)
MBS8228581-15nmol 15nmol
EUR 405

TCIRG1 siRNA (Human)
MBS8228581-30nmol 30nmol
EUR 565

TCIRG1 siRNA (Human)
MBS8228581-5x30nmol 5x30nmol
EUR 2450

anti- TCIRG1 antibody
FNab08558 100µg
EUR 658.5
Description: Antibody raised against TCIRG1

EP Reagent Methoxyphenylacetic Reagent - 100ML
1053601 100ML
EUR 490.05

Protein expression
CRO-4-Ind each Ask for price

TCIRG1 cloning plasmid
CSB-CL615690HU-10ug 10ug
EUR 969.6
Description: A cloning plasmid for the TCIRG1 gene.

EP Reagent Phosphomolybdotungstic Reagent - 100ML
1065000 100ML
EUR 226.8

RFP expression Adenovirus, in vivo ready
AVP001-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made RFP expression adenovirus, provided in PBS solution.

CFP expression Adenovirus, in vivo ready
AVP002-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made CFP expression adenovirus, provided in PBS solution.

GFP expression Adenovirus, in vivo ready
AVP011-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made GFP expression adenovirus, provided in PBS solution.

YFP expression Adenovirus, in vivo ready
AVP012-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made YFP expression adenovirus, provided in PBS solution.

BFP expression Adenovirus, in vivo ready
AVP017-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made BFP expression adenovirus, provided in PBS solution.

TCIM (NM_020130) Human Over-expression Lysate
E45H11034-2 each
EUR 395

TCIM (NM_020130) Human Over-expression Lysate
LS056892 100ug
EUR 628
Description: Transient overexpression lysate of chromosome 8 open reading frame 4 (C8orf4)

AVIDIN/BIOTIN BLOCKING REAGENT Reagent
GWB-Q00289 30 ml Ask for price

Gordon-McLeod Reagent (Oxidase reagent)
R026-100ML 1 unit
EUR 7.76
Description: Gordon-McLeod Reagent (Oxidase reagent)

Oxidase Reagent (Gordon-Macleod Reagent)
76207 100 ml
EUR 3.38
Description: Part B

YLEX Expression Kit
FYY201-1KT 1 kit Ask for price

TCIRG1 Polyclonal Antibody
28940-100ul 100ul
EUR 302.4

TCIRG1 Polyclonal Antibody
28940-50ul 50ul
EUR 224.4

TCIRG1 Polyclonal Antibody
E-AB-65293-120uL 120uL
EUR 320
Description: Unconjugated

TCIRG1 Polyclonal Antibody
E-AB-65293-200uL 200uL
EUR 530
Description: Unconjugated

TCIRG1 Polyclonal Antibody
E-AB-65293-60uL 60uL
EUR 200
Description: Unconjugated

TCIRG1 Polyclonal Antibody
E-AB-65293-each each Ask for price
Description: Unconjugated

Polyclonal TCIRG1 Antibody
APR10389G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TCIRG1 . This antibody is tested and proven to work in the following applications:

TCIRG1 polyclonal antibody
BS72582 50 ul
EUR 358
Description: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

TCIRG1 Polyclonal Antibody
E915382 100ul
EUR 225
Description: Available in various conjugation types.

TCIRG1 Polyclonal Antibody
MBS2555667-006mL 0.06mL
EUR 190

TCIRG1 Polyclonal Antibody
MBS2555667-012mL 0.12mL
EUR 265

TCIRG1 Polyclonal Antibody
MBS2555667-02mL 0.2mL
EUR 415

TCIRG1 Polyclonal Antibody
MBS2555667-5x02mL 5x0.2mL
EUR 1835

TCIRG1 Polyclonal Antibody
MBS9135368-002mL 0.02mL
EUR 200

TCIRG1 Polyclonal Antibody
MBS9135368-005mL 0.05mL
EUR 255

TCIRG1 Polyclonal Antibody
MBS9135368-01mL 0.1mL
EUR 345

TCIRG1 Polyclonal Antibody
MBS9135368-02mL 0.2mL
EUR 545

TCIRG1 Polyclonal Antibody
MBS9135368-5x02mL 5x0.2mL
EUR 2265

TCIRG1 Polyclonal Antibody
MBS8570064-01mL 0.1mL
EUR 305

TCIRG1 Polyclonal Antibody
MBS8570064-01mLAF405L 0.1mL(AF405L)
EUR 565

TCIRG1 Polyclonal Antibody
MBS8570064-01mLAF405S 0.1mL(AF405S)
EUR 565

TCIRG1 Polyclonal Antibody
MBS8570064-01mLAF610 0.1mL(AF610)
EUR 565

TCIRG1 Polyclonal Antibody
MBS8570064-01mLAF635 0.1mL(AF635)
EUR 565

TCIRG1 Polyclonal Antibody
MBS9432534-005mL 0.05mL
EUR 300

TCIRG1 Polyclonal Antibody
MBS9432534-01mL 0.1mL
EUR 390

TCIRG1 Polyclonal Antibody
MBS9432534-5x01mL 5x0.1mL
EUR 1610

TCIRG1 Polyclonal Antibody
RD82110A-120uL 120μL
EUR 360
Description: This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.

TCIRG1 Polyclonal Antibody
RD82110A-200uL 200μL
EUR 630
Description: This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.

TCIRG1 Polyclonal Antibody
RD82110A-60uL 60μL
EUR 204
Description: This gene encodes a subunit of a large protein complex known as a vacuolar H+-ATPase (V-ATPase). The protein complex acts as a pump to move protons across the membrane. This movement of protons helps regulate the pH of cells and their surrounding environment. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. Alternative splicing results in multiple transcript variants. Mutations in this gene are associated with infantile malignant osteopetrosis.

EP Reagent Sulfomolybdic Reagent R3 - 1L
1086500 1L
EUR 398.25

TRIpure Reagent (same as Trizol Reagent)
MBS356001-INQUIRE INQUIRE Ask for price

h OCT4 expression Adenovirus, in vivo ready
AVP013-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made adenovirus express human stem cell factor, OCT4, provided in PBS solution for in vivo application.

h SOX2 expression Adenovirus, in vivo ready
AVP014-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made adenovirus express human stem cell factor, SOX2, provided in PBS solution for in vivo application.

293 Expression MAX-1
EXP-711-11 1ml
EUR 218
Description: 293 Expression MAX-1 is expressed from - -.

h LIN28 expression Adenovirus, in vivo ready
AVP015-PBS 1x1011 IFU/ml x 50ul
EUR 455
Description: pre-made adenovirus express human stem cell factor, LIN28, provided in PBS solution for in vivo application.

Human TCIRG1 ELISA KIT
ELI-51415h 96 Tests
EUR 988.8

TCIRG1 ELISA KIT|Human
EF003500 96 Tests
EUR 826.8

Total RNA Isolation Reagent (Reagent Based)
MBS402052-100mL 100mL
EUR 235

Total RNA Isolation Reagent (Reagent Based)
MBS402052-4Reactions 4Reactions
EUR 165

CNGA2 Expression vector
60642 20 µg
EUR 900
Description: The CNGA2 expression vector is designed to express human cyclic nucleotide-gated cation channel 2 (CNGA2) in mammalian cells.

CNGA2 Expression vector
GWB-PSFA61 20ug Ask for price

Genomic DNA Isolation Reagent (Reagent Based)
MBS402050-100mL 100mL
EUR 255

Genomic DNA Isolation Reagent (Reagent Based)
MBS402050-4Reactions 4Reactions
EUR 185

TCIRG1 Antibody (C-Term)
E45R33601G-1 100 ul
EUR 395

TCIRG1 Antibody (C-Term)
E45R33601G-4 50 ul
EUR 295

TCIRG1 Antibody (C-Term)
MBS9231252-005mL 0.05mL
EUR 210

TCIRG1 Antibody (C-Term)
MBS9231252-02mL 0.2mL
EUR 430

TCIRG1 Antibody (C-Term)
MBS9231252-5x02mL 5x0.2mL
EUR 1910

pYLEX1 - Expression Vector
FYY203-5MG 5mg Ask for price

LEXSYcon2.1 Expression Kit
EGE-1310ble 1Kit
EUR 979.85
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit
EGE-1310bsd 1Kit
EUR 979.85
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit
EGE-1310hyg 1Kit
EUR 979.85
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit
EGE-1310neo 1Kit
EUR 979.85
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit
EGE-1310pac 1Kit
EUR 979.85
Description: for constitutive cytosolic or secretory protein expression

LEXSYcon2.1 Expression Kit
EGE-1310sat 1Kit
EUR 979.85
Description: for constitutive cytosolic or secretory protein expression

Blunt E1 Expression Kit
abx098098-100l 100 µl
EUR 712.5

Blunt E1 Expression Kit
abx098098-10rxns 10 rxns
EUR 560.4

Blunt E1 Expression Kit
abx098098-1ml 1 ml Ask for price

Blunt E1 Expression Kit
abx098098-200l 200 µl Ask for price

Blunt E2 Expression Kit
abx098873-100l 100 µl
EUR 712.5

Blunt E2 Expression Kit
abx098873-10rxns 10 rxns
EUR 560.4

Blunt E2 Expression Kit
abx098873-1ml 1 ml Ask for price

Blunt E2 Expression Kit
abx098873-200l 200 µl Ask for price

RFP expression Adenovirus
AVP001 1x109 IFU/ml x 200ul
EUR 206.5
Description: pre-made RFP expression adenovirus, provided in DMEM medium.

CFP expression Adenovirus
AVP002 1x109 IFU/ml x 200ul
EUR 206.5
Description: pre-made CFP expression adenovirus, provided in DMEM medium.

GFP expression Adenovirus
AVP011 1x109 IFU/ml x 200ul
EUR 206.5
Description: pre-made GFP expression adenovirus, provided in DMEM medium.

YFP expression Adenovirus
AVP012 1x109 IFU/ml x 200ul
EUR 206.5
Description: pre-made YFP expression adenovirus, provided in DMEM medium.

BFP expression Adenovirus
AVP017 1x109 IFU/ml x 200ul
EUR 206.5
Description: pre-made BFP expression adenovirus, provided in DMEM medium.

Human TCIRG1 shRNA Plasmid
20-abx956986
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

LEXSinduce3 Expression Kit
EGE-1410ble 1Kit
EUR 2296.43
Description: for inducible cytosolic or secretory protein expression

LEXSinduce3 Expression Kit
EGE-1410blecherry 1Kit
EUR 2296.43
Description: for inducible cytosolic or secretory protein expression

LEXSinduce3 Expression Kit
EGE-1410neo 1Kit
EUR 2296.43
Description: for inducible cytosolic or secretory protein expression

LEXSinduce4 Expression Kit
EGE-1420blecherry 1Kit
EUR 2296.43
Description: for inducible cytosolic or secretory protein expression

Rac1 Expression Vector Set
STA-454 1 kit
EUR 1765.2
Description: Rac1 Expression Vector Set contains 3 vectors: Rac wild type, T17N dominant negative mutant, and G12V constitutively active mutant.

RhoA Expression Vector Set
STA-456 1 kit
EUR 1765.2
Description: RhoA Expression Vector Set contains 3 vectors: RhoA wild type, T19N dominant negative mutant, and G14V constitutively active mutant.

Plant Total RNA Isolation Reagent (Reagent Based)
MBS402053-100mL 100mL
EUR 245

Plant Total RNA Isolation Reagent (Reagent Based)
MBS402053-4Reactions 4Reactions
EUR 165

TCIRG1 Antibody, HRP conjugated
1-CSB-PA615690LB01HU
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against TCIRG1. Recognizes TCIRG1 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

TCIRG1 Antibody, HRP conjugated
MBS7110104-005mg 0.05mg
EUR 190

TCIRG1 Antibody, HRP conjugated
MBS7110104-01mg 0.1mg
EUR 270

TCIRG1 Antibody, HRP conjugated
MBS7110104-5x01mg 5x0.1mg
EUR 1205

OPN expression inhibitor 1
HY-146064 10 mg
EUR 2272.76
Description: OPN expression inhibitor 1 (Compound 11) is an osteopontin (OPN) expression inhibitor. OPN expression inhibitor 1 can be used for breast cancer research[1].

OPN expression inhibitor 1
T62820-10mg 10mg Ask for price
Description: OPN expression inhibitor 1

OPN expression inhibitor 1
T62820-1g 1g Ask for price
Description: OPN expression inhibitor 1

OPN expression inhibitor 1
T62820-1mg 1mg Ask for price
Description: OPN expression inhibitor 1

OPN expression inhibitor 1
T62820-50mg 50mg Ask for price
Description: OPN expression inhibitor 1

OPN expression inhibitor 1
T62820-5mg 5mg Ask for price
Description: OPN expression inhibitor 1

Cdc42 Expression Vector Set
STA-455 1 kit
EUR 1765.2
Description: Cdc42 Expression Vector Set contains 3 vectors: Cdc42 wild type, T17N dominant negative mutant, and Q61L constitutively active mutant.

TCIRG1 Antibody, FITC conjugated
1-CSB-PA615690LC01HU
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against TCIRG1. Recognizes TCIRG1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

TCIRG1 Antibody, FITC conjugated
MBS7110105-005mg 0.05mg
EUR 190

TCIRG1 Antibody, FITC conjugated
MBS7110105-01mg 0.1mg
EUR 270
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