Hevert-Arzneimittel Assay,Blocking,ELISA kit Beleuchtung molekularer Bahnen bei Multiple

Beleuchtung molekularer Bahnen bei Multiple


hvr-ev

Beleuchtung molekularer Bahnen bei A number of-Sklerose-Läsionen und Immunmechanismus der Matrinenbehandlung bei EAE, einem Mausmodell für MS 

The etiology of a number of sclerosis (MS) is not clear, and the therapy of MS presents an ideal problem. This examine aimed to analyze the pathogenesis and potential therapeutic targets of MS and to outline goal genes of matrine, a quinolizidine alkaloid part derived from the basis of Sophorae flavescens that successfully suppressed experimental autoimmune encephalomyelitis (EAE), an animal mannequin of MS. To this finish, the GSE108000 gene information set within the Gene Expression Omnibus Database, which included 7 power energetic MS lesions and 10 management samples of white matter, was analyzed for differentially expressed genes (DEGs). X cell was used to investigate the microenvironmental variations in mind tissue samples of MS sufferers, together with 64 sorts of immune cells and stromal cells.

The organic features and enriched signaling pathways of DEGs have been analyzed by a number of approaches, together with GO, KEGG, GSEA, and GSVA. The outcomes by X cell confirmed considerably elevated numbers of immune cell populations within the MS lesions, with decreased erythrocytes, megakaryocytes, adipocytes, keratinocytes, endothelial cells, Th1 cells and Tregs. In GSE108000, there have been 637 DEGs, together with 428 up-regulated and 209 down-regulated genes. Potential goal genes of matrine have been then predicted by the community pharmacology methodology of Conventional Chinese language drugs, and 12 key genes have been obtained by cross evaluation of the goal genes of matrine and DEGs in MS lesions.

Lastly, we confirmed by RT-PCR the expected expression of those genes in mind tissues of matrine-treated EAE mice. Amongst these genes, 2 have been considerably downregulated and 6 upregulated by matrine therapy, and the importance of this gene regulation was additional investigated. In conclusion, our examine outlined a number of attainable matrine goal genes, which may be additional elucidated as mechanism(s) of matrine motion, and novel targets within the therapy of MS.

hvr-ev

hvr-ev

AIRE Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV624567 1.0 ug DNA
EUR 888

AIRE Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV624568 1.0 ug DNA
EUR 888

AIRN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV718409 1.0 ug DNA Ask for price

AIRE Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV624569 1.0 ug DNA
EUR 818.4

AIRE Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV624570 1.0 ug DNA
EUR 818.4

AIRN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV718410 1.0 ug DNA Ask for price

XM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756071 1.0 ug DNA Ask for price

XS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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S7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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CS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV709011 1.0 ug DNA
EUR 379.2

IV Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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NA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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NM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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MS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV734267 1.0 ug DNA Ask for price

C5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV704421 1.0 ug DNA
EUR 540

HP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703719 1.0 ug DNA
EUR 540

NP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV814299 1.0 ug DNA
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TYS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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VCF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755573 1.0 ug DNA Ask for price

VDI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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WSN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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WT2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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WTS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755999 1.0 ug DNA Ask for price

WWS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756017 1.0 ug DNA Ask for price

XCE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756041 1.0 ug DNA Ask for price

XGR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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XIC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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RSS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747629 1.0 ug DNA Ask for price

S11 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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S12 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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SDU Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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SEA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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RP6 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747185 1.0 ug DNA Ask for price

PRD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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PRS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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PDR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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PIH Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV740315 1.0 ug DNA Ask for price

mF4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732743 1.0 ug DNA Ask for price

CPP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV759281 1.0 ug DNA
EUR 2148

CPQ Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV759287 1.0 ug DNA
EUR 686.4

FTX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV761753 1.0 ug DNA
EUR 1104

LY9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705291 1.0 ug DNA
EUR 540

DUT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705459 1.0 ug DNA
EUR 540

NPL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705585 1.0 ug DNA
EUR 540

BMF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705639 1.0 ug DNA
EUR 540

FTO Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705999 1.0 ug DNA
EUR 540

MIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV706503 1.0 ug DNA
EUR 540

ATD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV719171 1.0 ug DNA Ask for price

GCY Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV726557 1.0 ug DNA Ask for price

GTS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV727145 1.0 ug DNA Ask for price

CCT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV720665 1.0 ug DNA Ask for price

CCV Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV720719 1.0 ug DNA Ask for price

CHR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721169 1.0 ug DNA Ask for price

HPT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV728723 1.0 ug DNA Ask for price

HTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV728969 1.0 ug DNA Ask for price

HMI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV728375 1.0 ug DNA Ask for price

F7R Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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FND Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV725471 1.0 ug DNA Ask for price

CMM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721403 1.0 ug DNA Ask for price

CNC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721451 1.0 ug DNA Ask for price

COP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721595 1.0 ug DNA Ask for price

CRG Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721781 1.0 ug DNA Ask for price

CRS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

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CSE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721835 1.0 ug DNA Ask for price

CTD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721919 1.0 ug DNA Ask for price

DCE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV722333 1.0 ug DNA Ask for price

DDU Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV722357 1.0 ug DNA Ask for price

DWS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723515 1.0 ug DNA Ask for price

EBM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723683 1.0 ug DNA Ask for price

EGI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723929 1.0 ug DNA Ask for price

DM1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723179 1.0 ug DNA Ask for price

MPI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712365 1.0 ug DNA
EUR 379.2

TK1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715875 1.0 ug DNA
EUR 379.2

TTK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV716385 1.0 ug DNA
EUR 379.2

UBB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV716529 1.0 ug DNA
EUR 379.2

WAC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV716727 1.0 ug DNA
EUR 379.2

AFA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV718313 1.0 ug DNA Ask for price

AIC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV718391 1.0 ug DNA Ask for price

AOM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV718865 1.0 ug DNA Ask for price

PTS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV713985 1.0 ug DNA
EUR 379.2

RGR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV714303 1.0 ug DNA
EUR 379.2

Sp2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715317 1.0 ug DNA
EUR 379.2

Sp2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715323 1.0 ug DNA
EUR 379.2

Syk Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715605 1.0 ug DNA
EUR 379.2

HGF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV701979 1.0 ug DNA
EUR 540

C8A Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV702501 1.0 ug DNA
EUR 540

EVL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV709839 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710247 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710253 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710259 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710265 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710271 1.0 ug DNA
EUR 379.2

FUZ Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710289 1.0 ug DNA
EUR 379.2

GIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710403 1.0 ug DNA
EUR 379.2

GRN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710661 1.0 ug DNA
EUR 379.2

CGA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708669 1.0 ug DNA
EUR 379.2

CKB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708753 1.0 ug DNA
EUR 379.2

CRK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708987 1.0 ug DNA
EUR 379.2

CRP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708993 1.0 ug DNA
EUR 379.2

CRP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708999 1.0 ug DNA
EUR 379.2

DTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV709467 1.0 ug DNA
EUR 379.2

NF2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712731 1.0 ug DNA
EUR 379.2

NMI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712773 1.0 ug DNA
EUR 379.2

OAT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712983 1.0 ug DNA
EUR 379.2

OS9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV713019 1.0 ug DNA
EUR 379.2

PIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV713469 1.0 ug DNA
EUR 379.2

HGF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710829 1.0 ug DNA
EUR 379.2

HGF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710835 1.0 ug DNA
EUR 379.2

HYI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV711141 1.0 ug DNA
EUR 379.2

JTB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV711555 1.0 ug DNA
EUR 379.2

LBH Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV711897 1.0 ug DNA
EUR 379.2

LTF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712071 1.0 ug DNA
EUR 379.2

LUM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712083 1.0 ug DNA
EUR 379.2

LXN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712089 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712167 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712173 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712179 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712185 1.0 ug DNA
EUR 379.2

OED Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736703 1.0 ug DNA Ask for price

KSS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730745 1.0 ug DNA Ask for price

KWE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730751 1.0 ug DNA Ask for price

LCO Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730883 1.0 ug DNA Ask for price

JBS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730193 1.0 ug DNA Ask for price

JPD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730199 1.0 ug DNA Ask for price

KFM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730349 1.0 ug DNA Ask for price

KMS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730469 1.0 ug DNA Ask for price

NSX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736493 1.0 ug DNA Ask for price

NT3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736499 1.0 ug DNA Ask for price

OAP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736655 1.0 ug DNA Ask for price

MAA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732365 1.0 ug DNA Ask for price

MCO Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732641 1.0 ug DNA Ask for price

MEB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732671 1.0 ug DNA Ask for price

MPE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV733739 1.0 ug DNA Ask for price

MSD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV734285 1.0 ug DNA Ask for price

MLS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV733631 1.0 ug DNA Ask for price

MOK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV733685 1.0 ug DNA Ask for price

AEN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707157 1.0 ug DNA
EUR 379.2

AEN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707163 1.0 ug DNA
EUR 379.2

AGK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707187 1.0 ug DNA
EUR 379.2

ALB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707271 1.0 ug DNA
EUR 379.2

ANG Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707325 1.0 ug DNA
EUR 379.2

ATM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707655 1.0 ug DNA
EUR 379.2

BID Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707847 1.0 ug DNA
EUR 379.2

BMF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707871 1.0 ug DNA
EUR 379.2

BMF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707877 1.0 ug DNA
EUR 379.2

CA8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708255 1.0 ug DNA
EUR 379.2

CA8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708261 1.0 ug DNA
EUR 379.2

CBS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708339 1.0 ug DNA
EUR 379.2

CBS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708345 1.0 ug DNA
EUR 379.2

FGA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV704103 1.0 ug DNA
EUR 540

NNT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV704253 1.0 ug DNA
EUR 379.2

SLN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV702969 1.0 ug DNA
EUR 540

CRP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703479 1.0 ug DNA
EUR 540

NPL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703695 1.0 ug DNA
EUR 540

LY9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703815 1.0 ug DNA
EUR 540

TDD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV750293 1.0 ug DNA Ask for price

THM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV750401 1.0 ug DNA Ask for price

TOC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV750677 1.0 ug DNA Ask for price

ST2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV749651 1.0 ug DNA
EUR 686.4

ST3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV749657 1.0 ug DNA Ask for price

ST4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV749669 1.0 ug DNA Ask for price

ST8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV749687 1.0 ug DNA Ask for price

TKT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV807481 1.0 ug DNA
EUR 379.2

TKT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV807487 1.0 ug DNA
EUR 379.2

DCI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV809319 1.0 ug DNA
EUR 379.2

RIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV812619 1.0 ug DNA
EUR 379.2

HNT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV812739 1.0 ug DNA
EUR 379.2

GAS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV813447 1.0 ug DNA
EUR 379.2

NMB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV792189 1.0 ug DNA
EUR 379.2

RET Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV792597 1.0 ug DNA
EUR 379.2

SFN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV792783 1.0 ug DNA
EUR 379.2

PB1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV811119 1.0 ug DNA
EUR 379.2

GBL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV811197 1.0 ug DNA
EUR 379.2

UTX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV814419 1.0 ug DNA
EUR 540

PB1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV815385 1.0 ug DNA
EUR 540

NLP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV811935 1.0 ug DNA
EUR 379.2

DCI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV812301 1.0 ug DNA
EUR 379.2

TYRL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV754907 1.0 ug DNA Ask for price

UBL6 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755087 1.0 ug DNA Ask for price

UGP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755123 1.0 ug DNA Ask for price

VIS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755621 1.0 ug DNA Ask for price

VMD1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755627 1.0 ug DNA Ask for price

VRNI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755849 1.0 ug DNA Ask for price

VTNR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755879 1.0 ug DNA Ask for price

WBS2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755915 1.0 ug DNA Ask for price

Fibroblasten als Immunregulatoren bei Infektionen, Entzündungen und Krebs

cells behave, with tissue-resident fibroblasts rising as a key cell kind in regulating activation or suppression of an immune response. Fibroblasts are heterogeneous cells, encompassing functionally distinct populations, the phenotypes of which differ in accordance with their tissue of origin and sort of inciting illness. Their immunological properties are additionally numerous, starting from the upkeep of a potent inflammatory surroundings in power irritation to selling immunosuppression in malignancy, and encapsulating and incarcerating infectious brokers inside tissues.

On this Evaluate, we examine the mechanisms by which fibroblasts management native immune responses, in addition to the elements regulating their inflammatory and suppressive profiles, in several tissues and pathological settings. This cross-disease perspective highlights the significance of tissue context in figuring out fibroblast-immune cell interactions, in addition to potential therapeutic avenues to exploit this data for the advantage of sufferers with power an infection, irritation and most cancers.

Ibrutinib hat zeitabhängige On- und Off-Goal-Effekte auf Plasma-Biomarker und Immunzellen bei chronischer lymphatischer Leukämie 

Ibrutinib is a covalently binding inhibitor of the B-cell receptor signaling-mediator Bruton’s tyrosine kinase (BTK) with nice efficacy in power lymphocytic leukemia (CLL). Frequent unwanted effects like atrial fibrillation (AF), bleeding and infections may be brought on by ibrutinib’s inhibition of different kinases in non-B cells. 5-year follow-up of plasma biomarkers by proximity extension assay and immune cell numbers by circulate cytometry throughout ibrutinib therapy revealed that 86 of the 265 investigated plasma biomarkers considerably modified throughout therapy, 74 of which decreased.

Among the many 12 markers that elevated, 6 are related to cardiovascular ailments and subsequently doubtlessly concerned in ibrutinib-induced AF. Comparability between wholesome donors and X-linked agammaglobulinemia (XLA) sufferers, who’ve nonfunctional BTK and primarily lack B cells, confirmed indicative adjustments in 53 of the 265 biomarkers whereas none differed considerably. Therefore, neither B cells nor BTK-dependent pathways in different cells appear to affect the degrees of the studied plasma biomarkers in wholesome donors.

Concerning immune cells, absolutely the variety of T cells, together with subsets, decreased, paralleling the reducing tumor burden. T helper 1 (Th1) cell numbers dropped strongly, whereas Th2 cells remained comparatively secure, inflicting Th2-skewing. Thus, long-term ibrutinib therapy has a profound impression on the plasma proteome and immune cells in sufferers with CLL.

Analyse der Immunantworten auf abgeschwächtes Alcelaphin-Herpesvirus 1, formuliert mit und ohne Adjuvans 

The experimental vaccine for bovine malignant catarrhal fever consists of viable attenuated alcelaphine herpesvirus 1 (AlHV-1) derived by intensive tradition passage, mixed with an oil-in-water adjuvant, delivered intramuscularly. This immunisation technique was over 80% efficient in earlier experimental and area trials and safety seemed to be related to induction of virus-neutralising antibodies. Whether or not the vaccine virus is required to be viable on the level of immunisation and whether or not adjuvant is required to induce the suitable immune responses stays unclear.

To handle these points two research have been carried out, firstly to analyse immune responses within the presence and absence of adjuvant and secondly, to analyze immune responses to vaccines containing adjuvant plus viable or inactivated AlHV-1. The primary examine confirmed that viable attenuated AlHV-1 within the absence of adjuvant induced virus-specific antibodies however the titres of virus-neutralising antibodies have been considerably decrease than these induced by vaccine containing viable virus and adjuvant, suggesting adjuvant was required for optimum responses.

In distinction, the second examine discovered that the vaccine containing inactivated (>99.9%) AlHV-1 induced comparable ranges of virus-neutralising antibody to the equal formulation containing viable AlHV-1. Collectively these research recommend that the MCF vaccine acts as an antigen depot for induction of immune responses, requiring adjuvant and an acceptable antigen supply, which needn’t be viable virus. These observations could assist in directing the growth of other MCF vaccine formulations for distribution within the absence of an intensive chilly chain.

AIRE Antibody

ABD6603 100 ug
EUR 525.6

AIRE Antibody

AF0334 200ul
EUR 420

AIRE Antibody

32424-100ul 100ul
EUR 302.4

AIRE Antibody

33590-100ul 100ul
EUR 302.4

AIRE Antibody

33590-50ul 50ul
EUR 224.4

AIRE Antibody

AF6841 100ul
EUR 420

AIRE Antibody

1-CSB-PA001502HA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

AIRE Antibody

CSB-PA001502KA01HU- each
EUR 402
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

AIRE Antibody

CSB-PA001502KA01HU-100ul 100ul
EUR 466.8
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

AIRE Antibody

1-CSB-PA000839
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IF, ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/10000

AIRE Antibody

1-CSB-PA009261
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

AIRE Antibody

CSB-PA274868- each
EUR 402
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

AIRE Antibody

CSB-PA274868-100ul 100ul
EUR 379.2
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

AIRE Antibody

DF6603 200ul
EUR 420

AIRE Antibody

DF3026 200ul
EUR 420

AIRE Antibody

R32465 100 ug
EUR 356.15
Description: The autoimmune regulator (AIRE) is a protein that in humans is encoded by the AIRE gene. This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

AIRE Antibody

R34350-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Autoimmune regulator protein

AIRE Antibody

R34389-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy), APECED

AIRE Antibody

R35463-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Autoimmune regulator, APECED, Automimmune polyendocrinopathy candidiasis ectodermal dystrophy

Anti-AIRE/Aire 1 Antibody

A00558 100ul
EUR 476.4
Description: Rabbit Polyclonal AIRE/Aire 1 Antibody. Validated in IF, WB and tested in Human, Mouse.

anti- AIRE antibody

FNab00241 100µg
EUR 606.3
Description: Antibody raised against AIRE

AIRE antibody (Ser156)

70R-34454 100 ug
EUR 392.4
Description: Rabbit polyclonal AIRE antibody (Ser156)

Polyclonal AIRE Antibody

APR03336G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AIRE . This antibody is tested and proven to work in the following applications:

AIRE Antibody, HRP conjugated

1-CSB-PA001502HB01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

AIRE Antibody, FITC conjugated

1-CSB-PA001502HC01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

AIRE (pS156) Antibody

abx332932-100ul 100 ul
EUR 560.4

AIRE Antibody, Biotin conjugated

1-CSB-PA001502HD01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Polyclonal AIRE Antibody (Internal)

APG00998G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human AIRE (Internal). This antibody is tested and proven to work in the following applications:

Autoimmune regulator (AIRE) Antibody

48129-100ul 100ul
EUR 399.6

Autoimmune regulator (AIRE) Antibody

48129-50ul 50ul
EUR 286.8

Autoimmune regulator (AIRE) Antibody

48149-100ul 100ul
EUR 399.6

Autoimmune regulator (AIRE) Antibody

48149-50ul 50ul
EUR 286.8

Autoimmune Regulator (AIRE) Antibody

abx230241-100ug 100 ug
EUR 577.2

Autoimmune Regulator (AIRE) Antibody

20-abx312575
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Autoimmune Regulator (AIRE) Antibody

20-abx171376
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug

Autoimmune Regulator (AIRE) Antibody

20-abx325675
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Autoimmune Regulator (AIRE) Antibody

20-abx323992
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Autoimmune Regulator (AIRE) Antibody

20-abx013298
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Autoimmune Regulator (AIRE) Antibody

abx038141-100ug 100 ug
EUR 469.2

Autoimmune Regulator (AIRE) Antibody

abx019018-100ug 100 ug
EUR 410.4

Autoimmune Regulator (AIRE) Antibody

20-abx007582
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul

Autoimmune Regulator (AIRE) Antibody

20-abx001466
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Autoimmune Regulator (AIRE) Antibody

20-abx175527
  • EUR 1446.00
  • EUR 693.60
  • 1 mg
  • 200 ug

Autoimmune Regulator (AIRE) Antibody

20-abx175528
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

Autoimmune Regulator (AIRE) Antibody

20-abx175529
  • EUR 1479.60
  • EUR 710.40
  • 1 mg
  • 200 ug

Autoimmune Regulator (AIRE) Antibody

abx117155-100ug 100 ug
EUR 560.4

Autoimmune Regulator (AIRE) Antibody

abx331461-100ul 100 ul
EUR 510

AIRE Conjugated Antibody

C32424 100ul
EUR 476.4

AIRE-1 Polyclonal Antibody

ABP50619-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

AIRE-1 Polyclonal Antibody

ABP50619-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

AIRE-1 Polyclonal Antibody

ABP50619-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

AIRE-1 Polyclonal Antibody

ABP54773-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of AIRE-1 from Human. This AIRE-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156

AIRE-1 Polyclonal Antibody

ABP54773-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of AIRE-1 from Human. This AIRE-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156

AIRE-1 Polyclonal Antibody

ABP54773-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of AIRE-1 from Human. This AIRE-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156

AIRE-1 Polyclonal Antibody

40562-100ul 100ul
EUR 302.4

AIRE-1 Polyclonal Antibody

40562-50ul 50ul
EUR 224.4

AIRE-1 Polyclonal Antibody

ES1618-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

AIRE-1 Polyclonal Antibody

ES1618-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

AIRE-1 Polyclonal Antibody

ES5772-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

AIRE-1 Polyclonal Antibody

ES5772-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Polyclonal AIRE Antibody (C-Terminus)

APG00997G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human AIRE (C-Terminus). This antibody is tested and proven to work in the following applications:

Autoimmune Regulator (AIRE) Antibody (HRP)

20-abx312576
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

AIRE (Isoform 1) Antibody

abx432298-200ul 200 ul
EUR 460.8

Autoimmune Regulator (AIRE) Antibody (FITC)

20-abx312577
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Autoimmune Regulator (AIRE) Antibody (Biotin)

20-abx312578
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

AIRE (Phospho-Ser156) Antibody

11782-100ul 100ul
EUR 302.4

AIRE (Phospho-Ser156) Antibody

11782-50ul 50ul
EUR 224.4

AIRE-1 Polyclonal Conjugated Antibody

C40562 100ul
EUR 476.4

AIRE (Isoforms 1 + 2) Antibody

abx431084-200ul 200 ul
EUR 460.8

AIRE-1 (phospho Ser156) Polyclonal Antibody

ABP54772-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of AIRE-1 phospho Ser156) from Human. This AIRE-1 phospho Ser156) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the phosphorylation site of S156

AIRE-1 (phospho Ser156) Polyclonal Antibody

ABP54772-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of AIRE-1 phospho Ser156) from Human. This AIRE-1 phospho Ser156) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the phosphorylation site of S156

AIRE-1 (phospho Ser156) Polyclonal Antibody

ABP54772-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of AIRE-1 phospho Ser156) from Human. This AIRE-1 phospho Ser156) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the phosphorylation site of S156

AIRE-1 (phospho Ser156) Polyclonal Antibody

ES5771-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against AIRE-1 (phospho Ser156) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

AIRE-1 (phospho Ser156) Polyclonal Antibody

ES5771-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against AIRE-1 (phospho Ser156) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

AIRE (Isoforms 1 and 2) Antibody

abx432299-200ul 200 ul
EUR 460.8

Autoimmune regulator (AIRE) Conjugated Antibody

C48129 100ul
EUR 476.4

AIRE (Phospho-Ser156) Polyclonal Conjugated Antibody

C11782 100ul
EUR 476.4

AIRE siRNA

20-abx907108
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

AIRE siRNA

20-abx907109
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

Autoimmune Regulator Phospho-Ser156 (AIRE pS156) Antibody

20-abx323993
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Autoimmune Regulator Phospho-Ser156 (AIRE pS156) Antibody

20-abx012667
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

AIRE Peptide

45-225P 0.1 mg
EUR 405.6
Description: (CT) AIRE Peptide

AIRE Peptide

45-226P 0.1 mg
EUR 405.6
Description: (IN) AIRE Peptide

AIRE Peptide

45-227P 0.1 mg
EUR 405.6
Description: (IN) AIRE Peptide

AIRE Rabbit pAb

A1767-100ul 100 ul
EUR 369.6

AIRE Rabbit pAb

A1767-200ul 200 ul
EUR 550.8

AIRE Rabbit pAb

A1767-20ul 20 ul
EUR 219.6

AIRE Rabbit pAb

A1767-50ul 50 ul
EUR 267.6

AIRE Rabbit pAb

A14183-100ul 100 ul
EUR 369.6

AIRE Rabbit pAb

A14183-200ul 200 ul
EUR 550.8

AIRE Rabbit pAb

A14183-20ul 20 ul
EUR 219.6

AIRE Rabbit pAb

A14183-50ul 50 ul
EUR 267.6

AIRE (isoform 1)

GT41000 100 ug
EUR 568.8

AIRE Blocking Peptide

AF0334-BP 1mg
EUR 234

AIRE Blocking Peptide

20-abx062024
  • EUR 326.40
  • EUR 493.20
  • 1 mg
  • 5 mg

AIRE Blocking Peptide

DF6603-BP 1mg
EUR 234

AIRE Blocking Peptide

DF3026-BP 1mg
EUR 234

Rat AIRE ELISA Kit

ERA0534 96Tests
EUR 625.2

AIRE Cell ELISA Kit

abx595022-96tests 96 tests
EUR 764.4

Goat AIRE ELISA Kit

EGTA0534 96Tests
EUR 625.2

Mouse AIRE ELISA Kit

EMA0534 96Tests
EUR 625.2

Sheep AIRE ELISA Kit

ESA0534 96Tests
EUR 625.2

Human AIRE ELISA Kit

EHA0534 96Tests
EUR 625.2

AIRE ELISA KIT|Human

EF005361 96 Tests
EUR 826.8

Human AIRE ELISA Kit

ELA-E13302h 96 Tests
EUR 988.8

Monkey AIRE ELISA Kit

EMKA0534 96Tests
EUR 625.2

Bovine AIRE ELISA Kit

EBA0534 96Tests
EUR 625.2

Rabbit AIRE ELISA Kit

ERTA0534 96Tests
EUR 625.2

Canine AIRE ELISA Kit

ECA0534 96Tests
EUR 625.2

Porcine AIRE ELISA Kit

EPA0534 96Tests
EUR 625.2

Chicken AIRE ELISA Kit

ECKA0534 96Tests
EUR 625.2

Anserini AIRE ELISA Kit

EAA0534 96Tests
EUR 625.2

Human AIRE shRNA Plasmid

20-abx950227
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse AIRE shRNA Plasmid

20-abx969093
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

AIRE Recombinant Protein (Rat)

RP189656 100 ug Ask for price

AIRE Recombinant Protein (Human)

RP046219 100 ug Ask for price

AIRE Recombinant Protein (Mouse)

RP115070 100 ug Ask for price

Aire ORF Vector (Rat) (pORF)

ORF063220 1.0 ug DNA
EUR 607.2

Guinea Pig AIRE ELISA Kit

EGA0534 96Tests
EUR 625.2

AIRE ORF Vector (Human) (pORF)

ORF015407 1.0 ug DNA
EUR 486

Aire ORF Vector (Mouse) (pORF)

ORF038358 1.0 ug DNA
EUR 607.2

AIRE ELISA Kit (Mouse) (OKCD02354)

OKCD02354 96 Wells
EUR 1028.4
Description: Description of target: Transcription factor playing an essential role to promote self-tolerance in the thymus by regulating the expression of a wide array of self-antigens that have the commonality of being tissue-restricted in their expression pattern in the periphery, called tissue restricted antigens (TRA) (Probable). Binds to G-doublets in an A/T-rich environment; the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3' combined with a 5'-TTATTA-3' box. Binds to nucleosomes. Binds to chromatin and interacts selectively with histone H3 that is not methylated at 'Lys-4', not phosphorylated at 'Thr-3' and not methylated at 'Arg-2'. Functions as a sensor of histone H3 modifications that are important for the epigenetic regulation of gene expression. Mainly expressed by medullary thymic epithelial cells (mTECs), induces the expression of thousands of tissue-restricted proteins, which are presented on major histocompatibility complex class I (MHC-I) and MHC-II molecules to developing T-cells percolating through the thymic medulla. Also induces self-tolerance through other mechanisms such as the regulation of the mTEC differentiation program. Controls the medullary accumulation of thymic dendritic cells and the development of regulatory T-cell through the regulation of XCL1 expression. Regulates the production of CCR4 and CCR7 ligands in medullary thymic epithelial cells and alters the coordinated maturation and migration of thymocytes. In thimic B-cells, allows the presentation of licensing-dependent endogenous self-anitgen for negative selection. In secondary lymphoid organs, induces functional inactivation of CD4+ T-cells. Expressed by a distinct bone marrow-derived population, induces self-tolerance through a mechanism that does not require regulatory T-cells and is resitant to innate inflammatory stimuli.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.058 ng/mL

AIRE ELISA Kit (Human) (OKCD08086)

OKCD08086 96 Wells
EUR 1170
Description: Description of target: AIRE is a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript p;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.053ng/mL

Human Autoimmune Regulator (AIRE) Protein

20-abx652629
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Autoimmune Regulator (AIRE) Protein

20-abx652630
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Mouse Autoimmune Regulator (AIRE) Protein

20-abx652631
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Aire sgRNA CRISPR Lentivector set (Rat)

K6745901 3 x 1.0 ug
EUR 406.8

AIRE 3'UTR GFP Stable Cell Line

TU050527 1.0 ml
EUR 1672.8

Aire 3'UTR GFP Stable Cell Line

TU151596 1.0 ml Ask for price

Aire 3'UTR GFP Stable Cell Line

TU250439 1.0 ml Ask for price

Pig Autoimmune Regulator (AIRE) ELISA Kit

abx360670-96tests 96 tests
EUR 990

Aire sgRNA CRISPR Lentivector set (Mouse)

K4907801 3 x 1.0 ug
EUR 406.8

AIRE sgRNA CRISPR Lentivector set (Human)

K0063701 3 x 1.0 ug
EUR 406.8

Rat Autoimmune regulator(AIRE)ELISA kit

YLA1691RA-48T 48T
EUR 465

Rat Autoimmune regulator(AIRE)ELISA kit

YLA1691RA-96T 96T
EUR 600

Anti-AIRE antibody

PAab00241 100 ug
EUR 426

Anti-AIRE Antibody

PB9980 100ug/vial
EUR 400.8

Anti-AIRE antibody

STJ116116 100 µl
EUR 332.4
Description: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

Anti-AIRE antibody

STJ22559 100 µl
EUR 332.4
Description: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

Anti-AIRE antibody

STJ70203 100 µg
EUR 430.8

Anti-AIRE antibody

STJ70934 100 µg
EUR 430.8

Anti-AIRE antibody

STJ71077 100 µg
EUR 430.8

Human Autoimmune Regulator (AIRE) CLIA Kit

20-abx493615
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Autoimmune Regulator (AIRE) CLIA Kit

20-abx493616
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Autoimmune Regulator (AIRE) CLIA Kit

abx196471-96tests 96 tests
EUR 990

AIRE Colorimetric Cell-Based ELISA Kit

EKC1020 100ul
EUR 686.4

Mouse Autoimmune Regulator (AIRE) ELISA Kit

20-abx153694
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Autoimmune Regulator (AIRE) ELISA Kit

abx250784-96tests 96 tests
EUR 848.4

Human Autoimmune Regulator (AIRE) ELISA Kit

20-abx150773
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Autoimmune Regulator (AIRE) ELISA Kit

abx570732-96tests 96 tests
EUR 848.4

Mouse Autoimmune Regulator (AIRE) ELISA Kit

abx570926-96tests 96 tests
EUR 886.8

Human Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Hu-48T 48T
EUR 620.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Hu-96T 96T
EUR 807.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Mu-48T 48T
EUR 632.4
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Mu-96T 96T
EUR 825.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Human AIRE/ Autoimmune regulator ELISA Kit

E0100Hu 1 Kit
EUR 726

Human AIRE(Autoimmune regulator) ELISA Kit

EH1501 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

Mouse Autoimmune regulator, Aire ELISA KIT

ELI-11972m 96 Tests
EUR 1038

Human Autoimmune regulator, AIRE ELISA KIT

ELI-12083h 96 Tests
EUR 988.8

Human Autoimmune Regulator (AIRE) ELISA Kit

SEC322Hu-10x96wellstestplate 10x96-wells test plate
EUR 5677.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

SEC322Hu-1x48wellstestplate 1x48-wells test plate
EUR 572.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

SEC322Hu-1x96wellstestplate 1x96-wells test plate
EUR 766.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

SEC322Hu-5x96wellstestplate 5x96-wells test plate
EUR 3090.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

4-SEC322Hu
  • EUR 5738.40
  • EUR 3031.20
  • EUR 768.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Autoimmune Regulator (AIRE) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

SEC322Mu-10x96wellstestplate 10x96-wells test plate
EUR 5834.88
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

SEC322Mu-1x48wellstestplate 1x48-wells test plate
EUR 585.7
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

SEC322Mu-1x96wellstestplate 1x96-wells test plate
EUR 785.28
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

SEC322Mu-5x96wellstestplate 5x96-wells test plate
EUR 3173.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Autoimmune Regulator (AIRE) in Tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

4-SEC322Mu
  • EUR 5895.60
  • EUR 3114.00
  • EUR 786.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Autoimmune Regulator (AIRE) in samples from Tissue homogenates and other biological fluids. with no significant corss-reactivity with analogues from other species.

Human Autoimmune Regulator(AIRE)ELISA Kit

QY-E00071 96T
EUR 433.2

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-48Tests 48 Tests
EUR 652.8

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-96Tests 96 Tests
EUR 907.2

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-48Tests 48 Tests
EUR 668.4

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-96Tests 96 Tests
EUR 928.8

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-48Tests 48 Tests
EUR 625.2

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-96Tests 96 Tests
EUR 867.6

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-48Tests 48 Tests
EUR 639.6

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-96Tests 96 Tests
EUR 888

Human Autoimmune regulator(AIRE)ELISA kit

YLA4398HU-48T 48T
EUR 435

Human Autoimmune regulator(AIRE)ELISA kit

YLA4398HU-96T 96T
EUR 562.5

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-48T 48T
EUR 475.34
Description: tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-96T 96T
EUR 679.04
Description: tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-48T 48T
EUR 487.52
Description: tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-96T 96T
EUR 696.47
Description: tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-48T 48T
EUR 452.7
Description: tissue homogenates and other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-96T 96T
EUR 646.7
Description: tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-48T 48T
EUR 464.3
Description: tissue homogenates and other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-96T 96T
EUR 663.3
Description: tissue homogenates and other biological fluids.

Monkey Autoimmune Regulator (AIRE) ELISA Kit

abx359019-96tests 96 tests
EUR 990

Rabbit Autoimmune Regulator (AIRE) ELISA Kit

abx363707-96tests 96 tests
EUR 990

AIRE Protein Vector (Rat) (pPM-C-HA)

PV252880 500 ng
EUR 723.6

Chicken Autoimmune Regulator (AIRE) ELISA Kit

abx355828-96tests 96 tests
EUR 990

AIRE Protein Vector (Rat) (pPB-C-His)

PV252878 500 ng
EUR 723.6

AIRE Protein Vector (Rat) (pPB-N-His)

PV252879 500 ng
EUR 723.6

AIRE Protein Vector (Rat) (pPM-C-His)

PV252881 500 ng
EUR 723.6

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