Hevert-Arzneimittel Assay,Blocking,ELISA kit Beleuchtung molekularer Bahnen bei Multiple

Beleuchtung molekularer Bahnen bei Multiple


hvr-ev

Beleuchtung molekularer Bahnen bei A number of-Sklerose-Läsionen und Immunmechanismus der Matrinenbehandlung bei EAE, einem Mausmodell für MS 

The etiology of a number of sclerosis (MS) is not clear, and the therapy of MS presents an ideal problem. This examine aimed to analyze the pathogenesis and potential therapeutic targets of MS and to outline goal genes of matrine, a quinolizidine alkaloid part derived from the basis of Sophorae flavescens that successfully suppressed experimental autoimmune encephalomyelitis (EAE), an animal mannequin of MS. To this finish, the GSE108000 gene information set within the Gene Expression Omnibus Database, which included 7 power energetic MS lesions and 10 management samples of white matter, was analyzed for differentially expressed genes (DEGs). X cell was used to investigate the microenvironmental variations in mind tissue samples of MS sufferers, together with 64 sorts of immune cells and stromal cells.

The organic features and enriched signaling pathways of DEGs have been analyzed by a number of approaches, together with GO, KEGG, GSEA, and GSVA. The outcomes by X cell confirmed considerably elevated numbers of immune cell populations within the MS lesions, with decreased erythrocytes, megakaryocytes, adipocytes, keratinocytes, endothelial cells, Th1 cells and Tregs. In GSE108000, there have been 637 DEGs, together with 428 up-regulated and 209 down-regulated genes. Potential goal genes of matrine have been then predicted by the community pharmacology methodology of Conventional Chinese language drugs, and 12 key genes have been obtained by cross evaluation of the goal genes of matrine and DEGs in MS lesions.

Lastly, we confirmed by RT-PCR the expected expression of those genes in mind tissues of matrine-treated EAE mice. Amongst these genes, 2 have been considerably downregulated and 6 upregulated by matrine therapy, and the importance of this gene regulation was additional investigated. In conclusion, our examine outlined a number of attainable matrine goal genes, which may be additional elucidated as mechanism(s) of matrine motion, and novel targets within the therapy of MS.

hvr-ev

hvr-ev

CMV Control lentiviral particles (Neo)

CMV-Null-Neo 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Neomycin marker under RSV promoter.

CMV Control lentiviral particles (Puro)

CMV-Null-Puro 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Puromycin marker under RSV promoter.

CMV Control lentiviral particles (GFP-Bsd)

CMV-Null-GB 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Blasticidin fusion marker under RSV promoter.

CMV Control lentiviral particles (GFP-Puro)

CMV-Null-GP 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Puromycin fusion marker under RSV promoter.

CMV Control lentiviral particles (RFP-Bsd)

CMV-Null-RB 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Blasticidin fusion marker under RSV promoter.

CMV Control lentiviral particles (RFP-Puro)

CMV-Null-RP 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Puromycin fusion marker under RSV promoter.

AIRE Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

LV624565 1.0 ug DNA
EUR 682

CMV control lentivirus (Hygro)

CMV-Null-Hygro 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It has the hygromycin selection under RSV promoter.

CMV control lentivirus (Zeo)

CMV-Null-Zeo 1 x107 IFU/ml x 200ul
EUR 349
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It has the Zeocin selection under RSV promoter.

CMV Control lentiviral particles (Bsd) in PBS

CMV-Null-Bsd-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the blasticidin marker under RSV promoter. The virus was concentrated and provided in PBS solution.

CMV Control lentiviral particles (Neo) in PBS

CMV-Null-Neo-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Neomycin marker under RSV promoter. The virus was concentrated and provided in PBS solution.

CMV Control lentiviral particles (Puro) in PBS

CMV-Null-Puro-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the Puromycin marker under RSV promoter. The virus was concentrated and provided in PBS solution.

AIRE Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV624566 1.0 ug DNA
EUR 682

AIRE Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV624567 1.0 ug DNA
EUR 740

AIRE Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV624568 1.0 ug DNA
EUR 740

CMV Control lentiviral particles (GFP-Bsd) in PBS

CMV-Null-GB-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Blasticidin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution.

CMV Control lentiviral particles (GFP-Puro) in PBS

CMV-Null-GP-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the GFP-Puromycin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution.

CMV Control lentiviral particles (RFP-Bsd) in PBS

CMV-Null-RB-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Blasticidin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution.

CMV Control lentiviral particles (RFP-Puro) in PBS

CMV-Null-RP-PBS 1 x108 IFU/ml x 200ul
EUR 710
Description: Negative control lentivirus contains a null spacer insert under CMV promoter, serves as the negative control of lentivurs treatment for the specificity of any target expression effects. It also has the RFP-Puromycin fusion marker under RSV promoter. The virus was concentrated and provided in PBS solution.

DRD5P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723353 1.0 ug DNA Ask for price

DRD5P2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723359 1.0 ug DNA Ask for price

DSTNP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723383 1.0 ug DNA Ask for price

DSTNP3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723389 1.0 ug DNA Ask for price

DTX2P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723395 1.0 ug DNA Ask for price

DURS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723401 1.0 ug DNA Ask for price

DUSPP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723407 1.0 ug DNA Ask for price

DUTP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723413 1.0 ug DNA Ask for price

DUTP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723419 1.0 ug DNA Ask for price

DUTP4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723425 1.0 ug DNA Ask for price

DUTP5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723431 1.0 ug DNA Ask for price

DUTP6 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723437 1.0 ug DNA Ask for price

DUTP7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723443 1.0 ug DNA Ask for price

DUTP8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723449 1.0 ug DNA Ask for price

DUX4L8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723455 1.0 ug DNA Ask for price

DUX4L10 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723461 1.0 ug DNA Ask for price

DUX4L11 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723467 1.0 ug DNA Ask for price

DUX4L14 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723473 1.0 ug DNA Ask for price

DUX4L16 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723479 1.0 ug DNA Ask for price

DUX4L17 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723485 1.0 ug DNA Ask for price

DUX4L18 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723491 1.0 ug DNA Ask for price

DUX4L19 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723497 1.0 ug DNA Ask for price

DUXB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723503 1.0 ug DNA Ask for price

DVL1L1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723509 1.0 ug DNA Ask for price

DWS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723515 1.0 ug DNA Ask for price

DYNLL1P2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723521 1.0 ug DNA Ask for price

DYRK1AIP1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723527 1.0 ug DNA Ask for price

DYRK1AIP2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723533 1.0 ug DNA Ask for price

DYT2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723539 1.0 ug DNA Ask for price

DYT4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723545 1.0 ug DNA Ask for price

DYT7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723551 1.0 ug DNA Ask for price

DYT10 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723557 1.0 ug DNA Ask for price

DYT13 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723563 1.0 ug DNA Ask for price

DYT15 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723569 1.0 ug DNA Ask for price

DYT17 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723575 1.0 ug DNA Ask for price

DYT21 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723581 1.0 ug DNA Ask for price

DYT22 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723587 1.0 ug DNA Ask for price

DYX1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723593 1.0 ug DNA Ask for price

DYX2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723605 1.0 ug DNA Ask for price

DYX3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723611 1.0 ug DNA Ask for price

DYX4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723617 1.0 ug DNA Ask for price

DYX5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723623 1.0 ug DNA Ask for price

DYX6 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723629 1.0 ug DNA Ask for price

DYX7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723635 1.0 ug DNA Ask for price

DYX8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723641 1.0 ug DNA Ask for price

DYX9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723647 1.0 ug DNA Ask for price

E2F3P2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723659 1.0 ug DNA Ask for price

E2F4P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723665 1.0 ug DNA Ask for price

E11S Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723671 1.0 ug DNA Ask for price

EBM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723683 1.0 ug DNA Ask for price

EBR3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723689 1.0 ug DNA Ask for price

EBR4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723695 1.0 ug DNA Ask for price

EBVM1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723701 1.0 ug DNA Ask for price

EBVS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723707 1.0 ug DNA Ask for price

ECA1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723713 1.0 ug DNA Ask for price

ECEL1P1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723719 1.0 ug DNA Ask for price

ECEL1P3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723725 1.0 ug DNA Ask for price

EDDM3DP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723731 1.0 ug DNA Ask for price

EEC1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723737 1.0 ug DNA Ask for price

EEC2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723743 1.0 ug DNA Ask for price

EEF1A1P3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723749 1.0 ug DNA Ask for price

EEF1A1P4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723755 1.0 ug DNA Ask for price

EEF1A1P15 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723761 1.0 ug DNA Ask for price

EEF1A1P16 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723767 1.0 ug DNA Ask for price

EEF1A1P17 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723773 1.0 ug DNA Ask for price

EEF1A1P18 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723779 1.0 ug DNA Ask for price

EEF1A1P22 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723785 1.0 ug DNA Ask for price

EEF1A1P23 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723791 1.0 ug DNA Ask for price

EEF1A1P25 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723797 1.0 ug DNA Ask for price

EEF1A1P26 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723803 1.0 ug DNA Ask for price

EEF1A1P28 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723809 1.0 ug DNA Ask for price

EEF1A1P29 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723815 1.0 ug DNA Ask for price

EEF1A1P30 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723821 1.0 ug DNA Ask for price

EEF1A1P31 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723827 1.0 ug DNA Ask for price

EEF1A1P33 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723833 1.0 ug DNA Ask for price

EEF1A1P34 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723839 1.0 ug DNA Ask for price

EEF1A1P35 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723845 1.0 ug DNA Ask for price

EEF1A1P38 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723851 1.0 ug DNA Ask for price

EEF1A1P40 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723857 1.0 ug DNA Ask for price

EEF1A1P41 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723863 1.0 ug DNA Ask for price

Fibroblasten als Immunregulatoren bei Infektionen, Entzündungen und Krebs

cells behave, with tissue-resident fibroblasts rising as a key cell kind in regulating activation or suppression of an immune response. Fibroblasts are heterogeneous cells, encompassing functionally distinct populations, the phenotypes of which differ in accordance with their tissue of origin and sort of inciting illness. Their immunological properties are additionally numerous, starting from the upkeep of a potent inflammatory surroundings in power irritation to selling immunosuppression in malignancy, and encapsulating and incarcerating infectious brokers inside tissues.

On this Evaluate, we examine the mechanisms by which fibroblasts management native immune responses, in addition to the elements regulating their inflammatory and suppressive profiles, in several tissues and pathological settings. This cross-disease perspective highlights the significance of tissue context in figuring out fibroblast-immune cell interactions, in addition to potential therapeutic avenues to exploit this data for the advantage of sufferers with power an infection, irritation and most cancers.

Ibrutinib hat zeitabhängige On- und Off-Goal-Effekte auf Plasma-Biomarker und Immunzellen bei chronischer lymphatischer Leukämie 

Ibrutinib is a covalently binding inhibitor of the B-cell receptor signaling-mediator Bruton’s tyrosine kinase (BTK) with nice efficacy in power lymphocytic leukemia (CLL). Frequent unwanted effects like atrial fibrillation (AF), bleeding and infections may be brought on by ibrutinib’s inhibition of different kinases in non-B cells. 5-year follow-up of plasma biomarkers by proximity extension assay and immune cell numbers by circulate cytometry throughout ibrutinib therapy revealed that 86 of the 265 investigated plasma biomarkers considerably modified throughout therapy, 74 of which decreased.

Among the many 12 markers that elevated, 6 are related to cardiovascular ailments and subsequently doubtlessly concerned in ibrutinib-induced AF. Comparability between wholesome donors and X-linked agammaglobulinemia (XLA) sufferers, who’ve nonfunctional BTK and primarily lack B cells, confirmed indicative adjustments in 53 of the 265 biomarkers whereas none differed considerably. Therefore, neither B cells nor BTK-dependent pathways in different cells appear to affect the degrees of the studied plasma biomarkers in wholesome donors.

Concerning immune cells, absolutely the variety of T cells, together with subsets, decreased, paralleling the reducing tumor burden. T helper 1 (Th1) cell numbers dropped strongly, whereas Th2 cells remained comparatively secure, inflicting Th2-skewing. Thus, long-term ibrutinib therapy has a profound impression on the plasma proteome and immune cells in sufferers with CLL.

Analyse der Immunantworten auf abgeschwächtes Alcelaphin-Herpesvirus 1, formuliert mit und ohne Adjuvans 

The experimental vaccine for bovine malignant catarrhal fever consists of viable attenuated alcelaphine herpesvirus 1 (AlHV-1) derived by intensive tradition passage, mixed with an oil-in-water adjuvant, delivered intramuscularly. This immunisation technique was over 80% efficient in earlier experimental and area trials and safety seemed to be related to induction of virus-neutralising antibodies. Whether or not the vaccine virus is required to be viable on the level of immunisation and whether or not adjuvant is required to induce the suitable immune responses stays unclear.

To handle these points two research have been carried out, firstly to analyse immune responses within the presence and absence of adjuvant and secondly, to analyze immune responses to vaccines containing adjuvant plus viable or inactivated AlHV-1. The primary examine confirmed that viable attenuated AlHV-1 within the absence of adjuvant induced virus-specific antibodies however the titres of virus-neutralising antibodies have been considerably decrease than these induced by vaccine containing viable virus and adjuvant, suggesting adjuvant was required for optimum responses.

In distinction, the second examine discovered that the vaccine containing inactivated (>99.9%) AlHV-1 induced comparable ranges of virus-neutralising antibody to the equal formulation containing viable AlHV-1. Collectively these research recommend that the MCF vaccine acts as an antigen depot for induction of immune responses, requiring adjuvant and an acceptable antigen supply, which needn’t be viable virus. These observations could assist in directing the growth of other MCF vaccine formulations for distribution within the absence of an intensive chilly chain.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Mu-96T 96T
EUR 688
  • Should the Mouse Autoimmune Regulator (AIRE) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-48Tests 48 Tests
EUR 521

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-96Tests 96 Tests
EUR 723

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-48Tests 48 Tests
EUR 533

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-96Tests 96 Tests
EUR 740

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-48Tests 48 Tests
EUR 544

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-96Tests 96 Tests
EUR 756

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-48Tests 48 Tests
EUR 557

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-96Tests 96 Tests
EUR 774

Anti-AIRE/Aire 1 Antibody

A00558 100ul
EUR 397
Description: Rabbit Polyclonal AIRE/Aire 1 Antibody. Validated in IF, WB and tested in Human, Mouse.

AIRE Antibody

33590-100ul 100ul
EUR 252

AIRE Antibody

33590-50ul 50ul
EUR 187

AIRE Antibody

32424-100ul 100ul
EUR 252

AIRE Antibody

1-CSB-PA000839
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IF, ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/10000

AIRE Antibody

1-CSB-PA001502HA01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

AIRE Antibody

CSB-PA001502KA01HU-
EUR 335
  • Form: liquid
  • Buffer: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Affinity purification
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

AIRE Antibody

CSB-PA001502KA01HU-100ul 100ul
EUR 389
  • Form: liquid
  • Buffer: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Affinity purification
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

AIRE Antibody

DF3026 200ul
EUR 304
Description: AIRE Antibody detects endogenous levels of total AIRE.

AIRE Antibody

DF6603 200ul
EUR 304
Description: AIRE Antibody detects endogenous levels of total AIRE.

AIRE Antibody

CSB-PA274868-
EUR 335
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific
  • Show more
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

AIRE Antibody

CSB-PA274868-100ul 100ul
EUR 316
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific
  • Show more
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

AIRE antibody

70R-34455 100 ug
EUR 327
Description: Rabbit polyclonal AIRE antibody

AIRE antibody

70R-51449 100 ul
EUR 244
Description: Purified Polyclonal AIRE antibody

AIRE antibody

70R-33714 100 ug
EUR 327
Description: Rabbit polyclonal AIRE antibody

AIRE Antibody

AF0334 200ul
EUR 304
Description: AIRE antibody detects endogenous levels of total AIRE.

AIRE Antibody

1-CSB-PA009261
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

AIRE Antibody

ABF5471 100 ug
EUR 438

AIRE Antibody

ABD3026 100 ug
EUR 438

AIRE Antibody

ABD6603 100 ug
EUR 438

AIRE Antibody

ABF0334 100 ug
EUR 438

Polyclonal AIRE Antibody

APR03336G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AIRE . This antibody is tested and proven to work in the following applications:

AIRE antibody (Ser156)

70R-34454 100 ug
EUR 327
Description: Rabbit polyclonal AIRE antibody (Ser156)

AIRE Conjugated Antibody

C32424 100ul
EUR 397

AIRE (pS156) Antibody

abx332932-100ul 100 ul
EUR 467
  • Shipped within 5-10 working days.

anti- AIRE antibody

FNab00241 100µg
EUR 505.25
  • Recommended dilution: WB: 1:500-1:5000
  • IHC: 1:20-200
  • Immunogen: autoimmune regulator
  • Uniprot ID: O43918
  • Gene ID: 326
  • Research Area: Metabolism
Description: Antibody raised against AIRE

Anti-AIRE antibody

PAab00241 100 ug
EUR 355

Anti-AIRE Antibody

PB9980 100ug/vial
EUR 334

Anti-AIRE antibody

STJ116116 100 µl
EUR 277
Description: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

Anti-AIRE antibody

STJ22559 100 µl
EUR 277
Description: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

Anti-AIRE antibody

STJ70934 100 µg
EUR 359

Anti-AIRE antibody

STJ71077 100 µg
EUR 359

Anti-AIRE antibody

STJ70203 100 µg
EUR 359

AIRE siRNA

20-abx907108
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

AIRE siRNA

20-abx907109
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

Autoimmune regulator (AIRE) Antibody

48129-100ul 100ul
EUR 333

Autoimmune regulator (AIRE) Antibody

48129-50ul 50ul
EUR 239

Autoimmune regulator (AIRE) Antibody

48149-100ul 100ul
EUR 333

Autoimmune regulator (AIRE) Antibody

48149-50ul 50ul
EUR 239

AIRE (Phospho-Ser156) Antibody

11782-100ul 100ul
EUR 252

AIRE (Phospho-Ser156) Antibody

11782-50ul 50ul
EUR 187

AIRE-1 Polyclonal Antibody

40562-100ul 100ul
EUR 252

AIRE-1 Polyclonal Antibody

40562-50ul 50ul
EUR 187

AIRE Antibody, HRP conjugated

1-CSB-PA001502HB01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

AIRE Antibody, FITC conjugated

1-CSB-PA001502HC01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

AIRE Antibody, Biotin conjugated

1-CSB-PA001502HD01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Phospho-AIRE (Ser156) Antibody

CSB-PA217298-
EUR 335
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodie
  • Show more
Description: A polyclonal antibody against Phospho-AIRE (Ser156). Recognizes Phospho-AIRE (Ser156) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-AIRE (Ser156) Antibody

CSB-PA217298-100ul 100ul
EUR 362
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodie
  • Show more
Description: A polyclonal antibody against Phospho-AIRE (Ser156). Recognizes Phospho-AIRE (Ser156) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Autoimmune Regulator (AIRE) Antibody

20-abx007582
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

abx019018-100ug 100 ug
EUR 342
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

20-abx175527
  • EUR 1205.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.

Autoimmune Regulator (AIRE) Antibody

20-abx175528
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug
  • Please enquire.

Autoimmune Regulator (AIRE) Antibody

20-abx175529
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug
  • Please enquire.

Autoimmune Regulator (AIRE) Antibody

abx117155-100ug 100 ug
EUR 467
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

abx038141-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

20-abx171376
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug
  • Please enquire.

Autoimmune Regulator (AIRE) Antibody

20-abx013298
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Polyclonal AIRE Antibody (Internal)

APG00998G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human AIRE (Internal). This antibody is tested and proven to work in the following applications:

Phospho-AIRE (S156) Antibody

1-CSB-PA009259
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against Phospho-AIRE (S156). Recognizes Phospho-AIRE (S156) from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

Autoimmune Regulator (AIRE) Antibody

abx331461-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

20-abx325675
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

20-abx323992
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

AIRE (Isoform 1) Antibody

abx432298-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Autoimmune Regulator (AIRE) Antibody

20-abx312575
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

abx230241-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

AIRE-1 Polyclonal Antibody

ABP50619-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

AIRE-1 Polyclonal Antibody

ABP50619-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

AIRE-1 Polyclonal Antibody

ABP50619-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

AIRE-1 Polyclonal Antibody

ABP54773-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human. This AIRE-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156

AIRE-1 Polyclonal Antibody

ABP54773-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human. This AIRE-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156

AIRE-1 Polyclonal Antibody

ABP54773-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human. This AIRE-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156

Autoimmune Regulator (AIRE) Antibody

20-abx001466
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

AIRE-1 Polyclonal Antibody

ES1618-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

AIRE-1 Polyclonal Antibody

ES1618-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

AIRE-1 Polyclonal Antibody

ES5772-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

AIRE-1 Polyclonal Antibody

ES5772-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Anti-AIRE-1 antibody

STJ91518 200 µl
EUR 197
Description: Rabbit polyclonal to AIRE-1.

Anti-AIRE-1 antibody

STJ91519 200 µl
EUR 197
Description: Rabbit polyclonal to AIRE-1.

AIRE Rabbit pAb

A14183-100ul 100 ul
EUR 308

AIRE Rabbit pAb

A14183-200ul 200 ul
EUR 459

AIRE Rabbit pAb

A14183-20ul 20 ul
EUR 183

AIRE Rabbit pAb

A14183-50ul 50 ul
EUR 223

AIRE Blocking Peptide

DF3026-BP 1mg
EUR 195

AIRE Blocking Peptide

DF6603-BP 1mg
EUR 195

AIRE Blocking Peptide

20-abx062024
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg
  • Shipped within 5-10 working days.

AIRE Blocking Peptide

AF0334-BP 1mg
EUR 195

AIRE Rabbit pAb

A1767-100ul 100 ul
EUR 308

AIRE Rabbit pAb

A1767-200ul 200 ul
EUR 459

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