Hevert-Arzneimittel Assay,cDNA,exosome Gastrointestinale Mikroumgebung und die Darm

Gastrointestinale Mikroumgebung und die Darm


hvr-ev

Gastrointestinale Mikroumgebung und die Darm-Lungen-Achse in den Immunantworten von schwerem COVID-19 

The worldwide pandemic of coronavirus illness 2019 (COVID-19), brought on by extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an unprecedented menace to the human well being. A detailed affiliation of the digestive tract is implied by the excessive frequency of gastrointestinal syndromes amongst COVID-19 sufferers. A greater understanding of the function of intestinal microenvironment in COVID-19 immunopathology might be useful to enhance the management of COVID-19 related morbidity and mortality. This assessment summarizes the immune responses related to the severity of COVID-19, the present proof of SARS-CoV-2 intestinal tropism, and the potential involvement of intestine microenvironment in COVID-19 severity. Moreover, we talk about the therapeutic potential of probiotics in its place drugs to stop or alleviate extreme COVID-19 end result.

hvr-ev

hvr-ev

AIRE (Phospho-Ser156) Polyclonal Conjugated Antibody

C11782 100ul
EUR 397

AIRE-1 (phospho Ser156) Polyclonal Antibody

ABP54772-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human AIRE-1 around the phosphorylation site of S156
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 phospho Ser156) from Human. This AIRE-1 phospho Ser156) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the phosphorylation site of S156

AIRE-1 (phospho Ser156) Polyclonal Antibody

ABP54772-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human AIRE-1 around the phosphorylation site of S156
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 phospho Ser156) from Human. This AIRE-1 phospho Ser156) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the phosphorylation site of S156

AIRE-1 (phospho Ser156) Polyclonal Antibody

ABP54772-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human AIRE-1 around the phosphorylation site of S156
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 phospho Ser156) from Human. This AIRE-1 phospho Ser156) antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the phosphorylation site of S156

AIRE-1 (phospho Ser156) Polyclonal Antibody

ES5771-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against AIRE-1 (phospho Ser156) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

AIRE-1 (phospho Ser156) Polyclonal Antibody

ES5771-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against AIRE-1 (phospho Ser156) from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Autoimmune Regulator Phospho-Ser156 (AIRE pS156) Antibody

20-abx012667
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Autoimmune Regulator Phospho-Ser156 (AIRE pS156) Antibody

20-abx323993
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

AIRE (Phospho-Ser156) Colorimetric Cell-Based ELISA Kit

EKC2603 100ul
EUR 572

Phospho-AIRE (Ser156) Colorimetric Cell-Based ELISA Kit (OKAG02155)

OKAG02155 2 x 96 Wells
EUR 740
Description: Description of target: ;Species reactivity: Human: S156;Application: ELISA;Assay info: Assay Type: Cell-Based
Subtype: Phospho
Detection Method: Colorimetric 450 nm;Sensitivity:

Anti-Phospho-AIRE-1 (S156) antibody

STJ90618 200 µl
EUR 197
Description: Rabbit polyclonal to Phospho-AIRE-1 (S156).

Anti-AIRE/Aire 1 Antibody

A00558 100ul
EUR 397
Description: Rabbit Polyclonal AIRE/Aire 1 Antibody. Validated in IF, WB and tested in Human, Mouse.

Phospho-AIRE (S156) Antibody

1-CSB-PA009259
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against Phospho-AIRE (S156). Recognizes Phospho-AIRE (S156) from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

anti- AIRE antibody

FNab00241 100µg
EUR 505.25
  • Recommended dilution: WB: 1:500-1:5000
  • IHC: 1:20-200
  • Immunogen: autoimmune regulator
  • Uniprot ID: O43918
  • Gene ID: 326
  • Research Area: Metabolism
Description: Antibody raised against AIRE

Anti-AIRE antibody

PAab00241 100 ug
EUR 355

Anti-AIRE Antibody

PB9980 100ug/vial
EUR 334

Anti-AIRE antibody

STJ116116 100 µl
EUR 277
Description: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

Anti-AIRE antibody

STJ22559 100 µl
EUR 277
Description: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

Anti-AIRE antibody

STJ70934 100 µg
EUR 359

Anti-AIRE antibody

STJ71077 100 µg
EUR 359

Anti-AIRE antibody

STJ70203 100 µg
EUR 359

Human Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Hu-48T 48T
EUR 517
  • Should the Human Autoimmune Regulator (AIRE) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Hu-96T 96T
EUR 673
  • Should the Human Autoimmune Regulator (AIRE) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Mu-48T 48T
EUR 527
  • Should the Mouse Autoimmune Regulator (AIRE) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Mouse Autoimmune Regulator (AIRE) ELISA Kit

DLR-AIRE-Mu-96T 96T
EUR 688
  • Should the Mouse Autoimmune Regulator (AIRE) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Autoimmune Regulator (AIRE) in samples from tissue homogenates or other biological fluids.

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-48Tests 48 Tests
EUR 521

Human Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Hu-96Tests 96 Tests
EUR 723

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-48Tests 48 Tests
EUR 533

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RD-AIRE-Mu-96Tests 96 Tests
EUR 740

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-48Tests 48 Tests
EUR 544

Human Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Hu-96Tests 96 Tests
EUR 756

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-48Tests 48 Tests
EUR 557

Mouse Autoimmune Regulator (AIRE) ELISA Kit

RDR-AIRE-Mu-96Tests 96 Tests
EUR 774

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Anti-AIRE-1 antibody

STJ91518 200 µl
EUR 197
Description: Rabbit polyclonal to AIRE-1.

Anti-AIRE-1 antibody

STJ91519 200 µl
EUR 197
Description: Rabbit polyclonal to AIRE-1.

AIRE Antibody

33590-100ul 100ul
EUR 252

AIRE Antibody

33590-50ul 50ul
EUR 187

AIRE Antibody

32424-100ul 100ul
EUR 252

AIRE Antibody

1-CSB-PA000839
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: WB, IF, ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/10000

AIRE Antibody

1-CSB-PA001502HA01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

AIRE Antibody

CSB-PA001502KA01HU-
EUR 335
  • Form: liquid
  • Buffer: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Affinity purification
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

AIRE Antibody

CSB-PA001502KA01HU-100ul 100ul
EUR 389
  • Form: liquid
  • Buffer: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Affinity purification
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:2000, IHC:1:50-1:200

AIRE Antibody

DF3026 200ul
EUR 304
Description: AIRE Antibody detects endogenous levels of total AIRE.

AIRE Antibody

DF6603 200ul
EUR 304
Description: AIRE Antibody detects endogenous levels of total AIRE.

AIRE Antibody

CSB-PA274868-
EUR 335
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific
  • Show more
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

AIRE Antibody

CSB-PA274868-100ul 100ul
EUR 316
  • Form: liquid
  • Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific
  • Show more
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

AIRE antibody

70R-34455 100 ug
EUR 327
Description: Rabbit polyclonal AIRE antibody

AIRE antibody

70R-51449 100 ul
EUR 244
Description: Purified Polyclonal AIRE antibody

AIRE antibody

70R-33714 100 ug
EUR 327
Description: Rabbit polyclonal AIRE antibody

AIRE Antibody

AF0334 200ul
EUR 304
Description: AIRE antibody detects endogenous levels of total AIRE.

AIRE Antibody

1-CSB-PA009261
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/5000

AIRE Antibody

ABF5471 100 ug
EUR 438

AIRE Antibody

ABD3026 100 ug
EUR 438

AIRE Antibody

ABD6603 100 ug
EUR 438

AIRE Antibody

ABF0334 100 ug
EUR 438

Polyclonal AIRE Antibody

APR03336G 0.05ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human AIRE . This antibody is tested and proven to work in the following applications:

AIRE Conjugated Antibody

C32424 100ul
EUR 397

AIRE (pS156) Antibody

abx332932-100ul 100 ul
EUR 467
  • Shipped within 5-10 working days.

Polyclonal Goat Anti-AIRE (isoform 1) Antibody

APG00016G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-AIRE (isoform 1) . This antibody is tested and proven to work in the following applications:

AIRE siRNA

20-abx907108
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

AIRE siRNA

20-abx907109
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol
  • Shipped within 5-10 working days.

Autoimmune regulator (AIRE) Antibody

48129-100ul 100ul
EUR 333

Autoimmune regulator (AIRE) Antibody

48129-50ul 50ul
EUR 239

Autoimmune regulator (AIRE) Antibody

48149-100ul 100ul
EUR 333

Autoimmune regulator (AIRE) Antibody

48149-50ul 50ul
EUR 239

AIRE-1 Polyclonal Antibody

40562-100ul 100ul
EUR 252

AIRE-1 Polyclonal Antibody

40562-50ul 50ul
EUR 187

AIRE Antibody, HRP conjugated

1-CSB-PA001502HB01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

AIRE Antibody, FITC conjugated

1-CSB-PA001502HC01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

AIRE Antibody, Biotin conjugated

1-CSB-PA001502HD01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
  • Form: Liquid
  • Buffer: Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 >95%, Protein G purified
Description: A polyclonal antibody against AIRE. Recognizes AIRE from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Autoimmune Regulator (AIRE) Antibody

20-abx007582
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

abx019018-100ug 100 ug
EUR 342
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

20-abx175527
  • EUR 1205.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.

Autoimmune Regulator (AIRE) Antibody

20-abx175528
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug
  • Please enquire.

Autoimmune Regulator (AIRE) Antibody

20-abx175529
  • EUR 1233.00
  • EUR 592.00
  • 1 mg
  • 200 ug
  • Please enquire.

Autoimmune Regulator (AIRE) Antibody

abx117155-100ug 100 ug
EUR 467
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

abx038141-100ug 100 ug
EUR 391
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

20-abx171376
  • EUR 857.00
  • EUR 439.00
  • 1 mg
  • 200 ug
  • Please enquire.

Autoimmune Regulator (AIRE) Antibody

20-abx013298
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
  • Shipped within 5-10 working days.

Polyclonal AIRE Antibody (Internal)

APG00998G 0.05mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human AIRE (Internal). This antibody is tested and proven to work in the following applications:

Autoimmune Regulator (AIRE) Antibody

abx331461-100ul 100 ul
EUR 425
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

20-abx325675
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

20-abx323992
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug
  • Shipped within 5-10 working days.

AIRE (Isoform 1) Antibody

abx432298-200ul 200 ul
EUR 384
  • Shipped within 1-3 working days.

Autoimmune Regulator (AIRE) Antibody

20-abx312575
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
  • Shipped within 5-10 working days.

Autoimmune Regulator (AIRE) Antibody

abx230241-100ug 100 ug
EUR 481
  • Shipped within 5-12 working days.

AIRE-1 Polyclonal Antibody

ABP50619-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

AIRE-1 Polyclonal Antibody

ABP50619-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

AIRE-1 Polyclonal Antibody

ABP50619-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human, Mouse. This AIRE-1 antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human AIRE-1 at AA range: 60-140

AIRE-1 Polyclonal Antibody

ABP54773-003ml 0.03ml
EUR 158
  • Immunogen information: Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human. This AIRE-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156

AIRE-1 Polyclonal Antibody

ABP54773-01ml 0.1ml
EUR 289
  • Immunogen information: Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human. This AIRE-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156

AIRE-1 Polyclonal Antibody

ABP54773-02ml 0.2ml
EUR 414
  • Immunogen information: Synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156
  • Applications tips:
Description: A polyclonal antibody for detection of AIRE-1 from Human. This AIRE-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human AIRE-1 around the non-phosphorylation site of S156

Autoimmune Regulator (AIRE) Antibody

20-abx001466
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

AIRE-1 Polyclonal Antibody

ES1618-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

AIRE-1 Polyclonal Antibody

ES1618-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human/Mouse. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA

AIRE-1 Polyclonal Antibody

ES5772-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

AIRE-1 Polyclonal Antibody

ES5772-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against AIRE-1 from Human. This antibody is tested and validated for WB, ELISA, WB, ELISA

Polyclonal Goat Anti-AIRE (isoforms 1 + 2) Antibody

APG00017G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-AIRE (isoforms 1 + 2) . This antibody is tested and proven to work in the following applications:

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Polyclonal Goat Anti-AIRE (isoforms 1 and 2) Antibody

APG00018G 0.1mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-AIRE (isoforms 1 and 2) . This antibody is tested and proven to work in the following applications:

AIRE Rabbit pAb

A14183-100ul 100 ul
EUR 308

AIRE Rabbit pAb

A14183-200ul 200 ul
EUR 459

AIRE Rabbit pAb

A14183-20ul 20 ul
EUR 183

AIRE Rabbit pAb

A14183-50ul 50 ul
EUR 223

AIRE Blocking Peptide

DF3026-BP 1mg
EUR 195

AIRE Blocking Peptide

DF6603-BP 1mg
EUR 195

AIRE Blocking Peptide

20-abx062024
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg
  • Shipped within 5-10 working days.

Immunsystem und Methamphetamin: Molekulare Foundation einer Beziehung 

Use of methamphetamine (Meth) as a drug of abuse is on the rise worldwide. Moreover its impact on the operate of the mind, Meth has detrimental results on how the immune system capabilities. As documented within the literature, numerous experimental fashions (mobile, animal, mice, and non-human primates) have been used which have contributed to the general data about immune system impairments from Meth publicity. It must be famous that whereas Meth is utilized in very few therapies, it impacts a broad vary of organic mechanisms, not solely immune regulation, in a unfavorable method.

Undoubtfully, the impact of Meth is very complicated; furthermore, the preliminary molecular triggers stay unknown. Analyses of obtainable literature means that the impact of Meth just isn’t prompted by one underlying mechanism. Whether or not the impact of Meth is acute or long-lasting, the general impact is unfavorable. Additional development of our data on Meth’s particular actions would require systematic experimental approaches utilizing all out there fashions. As well as, bioinformatic analyses are crucial to construct a complete mannequin as a wanted software to fill the hole in data.

Fehlende Immunantwort nach mRNA-Impfung gegen SARS-CoV-2 bei einem Patienten mit Organtransplantation 

The current approval and distribution of vaccines towards SARS-CoV-2 has been a serious growth within the combat towards the present COVID-19 pandemic. The primary 2 vaccines accredited in the USA, mRNA-1273 and BNT162b2, are each mRNA primarily based and extremely efficient in immunocompetent individuals, however efficacy in sufferers on immunosuppressants has not been established. Moreover, knowledge suggests these sufferers are much less possible that immunocompetent individuals to develop neutralizing antibodies after COVID-19 an infection.

Given the excessive danger of poor outcomes in organ transplant and immunosuppressed sufferers, efficient vaccination is paramount on this group. We current the primary reported case of a SOT affected person who failed to attain seroconversion after 2 doses of mRNA vaccine. This case has important implications about how immunosuppressed sufferers ought to be endorsed about SARS-CoV-2 vaccination and the safety offered. Physicians ought to stay clinically suspicious for an infection with SARS-CoV-2 regardless of vaccination standing in stable organ transplant sufferers. This text is protected by copyright. All rights reserved.

Auswirkungen der Artesunat-Tablette auf die Immunaktivierung und -rekonstitution bei HAART-behandelten Patienten mit unvollständigen Immunantworten 

The extent of T cell activation is a greater predictor of CD4+ T cell depletion in extremely energetic anti-retroviral remedy (HAART)-treated sufferers than viral load. Artesunate is an artemisinin by-product that has an immunomodulatory impact. This examine investigated whether or not artesunate pill reduces T cell activation and improves immune reconstitution amongst sufferers with suboptimal immune restoration regardless of receiving long-term efficient HAART. This was a randomized, potential, parallel, open-label trial consisting of 45 individuals whose plasma HIV load was successfully suppressed by HAART for over 18 months and who had CD4+ T cell counts of lower than 300 cells/µL or a rise of lower than 20% from baseline.

The sufferers had been randomized 2:1 into the artesunate group or the management group and acquired artesunate tablets (orally, 50 mg two occasions each day) mixed with HAART or HAART alone, respectively. T-cell subsets, activation markers, scientific signs, viral load and unwanted effects had been assessed. By 48 weeks, artesunate pill didn’t enhance CD4+ T cell restoration or cut back the activation of T cell subsets however induced in a smaller decline within the expression of T cell activation markers amongst HAART-treated sufferers with incomplete immune responses. Nonetheless, artesunate pill did seem to cut back the extent of T cell apoptosis. One topic developed reasonable anaemia. Lengthy-term use of artesunate pill is unlikely to provide substantial scientific advantages in sufferers receiving HAART who exhibit an incomplete immune response.

Induktion von schützenden Immunantworten gegen eine letale Zika-Virus-Herausforderung nach der Impfung mit einem dualen Serotyp des rekombinanten vesikulären Stomatitis-Virus, der das genetisch veränderte Zika-Virus-E-Protein-Gen trägt

The event of a vaccine to stop Zika virus (ZIKV) an infection has been one of many priorities in infectious illness analysis lately. There have been quite a few makes an attempt to develop an efficient vaccine towards ZIKV. It’s crucial to decide on the most secure and the best ZIKV vaccine from all candidate vaccines to manage this an infection globally. Now we have employed a twin serotype of prime-boost recombinant vesicular stomatitis virus (VSV) vaccine technique, to develop a ZIKV vaccine candidate, utilizing a sort 1 IFN-receptor knock-out (Ifnar -/-) mouse mannequin for problem research.

Prime vaccination with an attenuated recombinant VSV Indiana serotype (rVSVInd) carrying a genetically modified ZIKV envelope (E) protein gene adopted by enhance vaccination with attenuated recombinant VSV New Jersey serotype (rVSVNJ) carrying the identical E gene induced sturdy adaptive immune responses. Particularly, rVSV carrying the ZIKV E gene with the honeybee melittin sign peptide (msp) on the N terminus and VSV G protein transmembrane area and cytoplasmic tail (Gtc) on the C terminus of the E gene induced sturdy protecting immune responses. This vaccine routine induced extremely potent neutralizing antibodies and T cell responses within the absence of an adjuvant and guarded Ifnar -/- mice from a deadly dose of the ZIKV problem.

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